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[骨肿瘤的X线诊断——基础知识与临床应用]

[Roentgenographic diagnosis of bone tumors--its basic knowledge and clinical application].

作者信息

Sato K, Miura T

机构信息

Department of Orthopaedic Surgery, Nagoya University School of Medicine.

出版信息

Rinsho Byori. 1991 Mar;39(3):223-9.

PMID:2051595
Abstract

Roentgenographic diagnosis of bone tumors is considered to be extremely important to decide whether a new patient should be biopsied immediately to make the proper diagnosis or the patient could be followed up without operative treatment. The basis knowledge important in making the proper decision on the roentgenogram of the bone tumor, are presented and four cases of bone tumors or tumor-like conditions are presented to show how such knowledge becomes useful. First of all, the basic knowledge based on the anatomical peculiarities are described. Chordoma deriving from the remnant tissue, notochord, should be placed in the midline of the body. Metaphyseal region of the growing child showed a local immune deficient state because of the special anatomic arrangement of the vascular structure for the sake of the open epiphyseal line. This is thought to be related with the high rate of primary malignant bone tumors in this area and in this age group, for example, osteosarcoma. Next, roentgenographic changes are described separately: intracortical changes, cortical changes, periosteal reaction and soft tissue extension. These changes are summarized to differentiate the benign lesion from the malignant one. Thirdly, the peculiar location of the tumor is described. Examples are giant cell tumor, chondroblastoma and clear cell chondrosarcoma in the epiphyseal region, osteoid osteoma, intracortical abscess and the osteofibrous dysplasia in the intracortical region.

摘要

骨肿瘤的X线诊断对于决定新患者是应立即进行活检以做出正确诊断,还是可在不进行手术治疗的情况下进行随访而言,被认为极为重要。本文介绍了在根据骨肿瘤的X线片做出正确决策时重要的基础知识,并展示了4例骨肿瘤或肿瘤样病变病例,以说明这些知识是如何发挥作用的。首先,描述基于解剖学特点的基础知识。源自残留组织脊索的脊索瘤应位于身体中线。由于为开放骨骺线而存在的血管结构的特殊解剖排列,正在生长的儿童的干骺端区域呈现局部免疫缺陷状态。这被认为与该区域和该年龄组原发性恶性骨肿瘤的高发生率有关,例如骨肉瘤。接下来,分别描述X线变化:皮质内变化、皮质变化、骨膜反应和软组织扩展。总结这些变化以区分良性病变和恶性病变。第三,描述肿瘤的特殊位置。例如,骨骺区域的骨巨细胞瘤、软骨母细胞瘤和透明细胞软骨肉瘤,皮质内区域的骨样骨瘤、皮质内脓肿和骨纤维发育不良。

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