Department of Traumatology, Hand and Reconstructive Surgery, Friedrich Schiller University Jena, Erlanger Allee 101, Jena, Germany.
J Bone Joint Surg Am. 2010 Jun;92(6):1442-52. doi: 10.2106/JBJS.H.01722.
Fixation of distal femoral fractures remains a challenge, especially in osteoporotic bone. This study was performed to investigate the biomechanical stability of four different fixation devices for the treatment of comminuted distal femoral fractures in osteoporotic bone.
Four fixation devices were investigated biomechanically under torsional and axial loading. Three intramedullary nails, differing in the mechanism of distal locking (with two lateral-to-medial screws in one construct, one screw and one spiral blade in another construct, and four screws [two oblique and two lateral-to-medial with medial nuts] in the third), and one angular stable plate were used. All constructs were tested in an osteoporotic synthetic bone model of an AO/ASIF type 33-C2 fracture. Two nail constructs (the one-screw and spiral blade construct and the four-screw construct) were also compared under axial loading in eight pairs of fresh-frozen human cadaveric femora.
The angular stable plate constructs had significantly higher torsional stiffness than the other constructs; the intramedullary nail with four-screw distal locking achieved nearly comparable results. Furthermore, the four-screw distal locking construct had the greatest torsional strength. Axial stiffness was also the highest for the four-screw distal locking device; the lowest values were achieved with the angular stable plate. The ranking of the constructs for axial cycles to failure was the four-screw locking construct, with the highest number of cycles, followed by the angular stable plate, the spiral blade construct, and two-screw fixation. The findings in the human cadaveric bone were comparable with those in the synthetic bone model. Failure modes under cyclic axial load were comparable for the synthetic and human bone models.
The findings of this study support the concept that, for intramedullary nails, the kind of distal interlocking pattern affects the stabilization of distal femoral fractures. Four-screw distal locking provides the highest axial stability and nearly comparable torsional stability to that of the angular stable plate; the four-screw distal interlocking construct was found to have the best combined (torsional and axial) biomechanical stability.
股骨远端骨折的固定仍然是一个挑战,尤其是在骨质疏松的骨骼中。本研究旨在研究四种不同的固定装置在治疗骨质疏松性股骨远端粉碎性骨折中的生物力学稳定性。
在扭转和轴向加载下对四种固定装置进行生物力学研究。三种髓内钉在远端锁定机制上有所不同(一种结构中有两个从外侧到内侧的螺钉,另一种结构中有一个螺钉和一个螺旋刀片,第三种结构中有四个螺钉[两个斜向和两个从外侧到内侧,带有内侧螺母]),以及一种角度稳定钢板。所有的固定装置都在 AO/ASIF 33-C2 型骨折的骨质疏松合成骨模型中进行了测试。两个钉固定装置(单螺钉和螺旋刀片固定装置和四螺钉固定装置)也在 8 对新鲜冷冻人体股骨标本的轴向加载下进行了比较。
角度稳定钢板固定装置的扭转刚度明显高于其他固定装置;四螺钉远端锁定的髓内钉获得了几乎相当的结果。此外,四螺钉远端锁定固定装置具有最大的扭转强度。四螺钉远端锁定装置的轴向刚度也最高;角度稳定钢板的轴向刚度最低。轴向失效周期的固定装置排名是四螺钉锁定装置,具有最高的周期数,其次是角度稳定钢板、螺旋刀片固定装置和双螺钉固定装置。在合成骨模型中,人体尸体骨骼的发现与在合成骨模型中的发现相当。在循环轴向载荷下的失效模式在合成和人体骨模型中是相似的。
本研究的结果支持这样一种观点,即对于髓内钉来说,远端锁定模式的类型会影响股骨远端骨折的稳定性。四螺钉远端锁定提供了最高的轴向稳定性和几乎与角度稳定钢板相当的扭转稳定性;四螺钉远端锁定固定装置被发现具有最佳的综合(扭转和轴向)生物力学稳定性。