Does obesity reduce load-induced muscle hypertrophy?
作者信息
Papasani Madhusudhan R, Thornton Kara, Yinggian Zhan, Brezas Andreas, Welch Cassie, Wang Guankui, Villasante Alejandro, Pokharel Deep, Cheguru Pallavi, Kotla Swathi, Julien Daniel C
机构信息
Department of Animal and Veterinary Science, University of Idaho, Moscow, ID 83844-2330, USA.
出版信息
J Physiol. 2010 Jun 1;588(Pt 11):1819-20. doi: 10.1113/jphysiol.2010.189357.
Abstract
摘要
相似文献
1
Does obesity reduce load-induced muscle hypertrophy?肥胖会减轻负荷诱导的肌肉肥大吗？
J Physiol. 2010 Jun 1;588(Pt 11):1819-20. doi: 10.1113/jphysiol.2010.189357.
2
Chronic high fat feeding attenuates load-induced hypertrophy in mice.慢性高脂肪喂养可减弱小鼠因负荷引起的肥大。
J Physiol. 2009 Dec 1;587(Pt 23):5753-65. doi: 10.1113/jphysiol.2009.180174. Epub 2009 Oct 12.
3
Muscle-to-fat interaction: a two-way street?肌肉与脂肪的相互作用：是双向的吗？
J Physiol. 2010 Jan 1;588(Pt 1):21. doi: 10.1113/jphysiol.2009.184747.
4
Altered expression and insulin-induced trafficking of Na+-K+-ATPase in rat skeletal muscle: effects of high-fat diet and exercise.大鼠骨骼肌中钠钾ATP酶的表达改变及胰岛素诱导的转运：高脂饮食和运动的影响
Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E38-49. doi: 10.1152/ajpendo.90990.2008. Epub 2009 Apr 14.
5
Transthyretin contributes to insulin resistance and diminishes exercise-induced insulin sensitivity in obese mice by inhibiting AMPK activity in skeletal muscle.甲状腺素运载蛋白通过抑制骨骼肌中的 AMPK 活性导致肥胖小鼠胰岛素抵抗，并减弱运动引起的胰岛素敏感性。
Am J Physiol Endocrinol Metab. 2021 Apr 1;320(4):E808-E821. doi: 10.1152/ajpendo.00495.2020. Epub 2021 Mar 8.
6
Resistance training enhances components of the insulin signaling cascade in normal and high-fat-fed rodent skeletal muscle.抗阻训练可增强正常及高脂喂养啮齿动物骨骼肌中胰岛素信号级联反应的各个组成部分。
J Appl Physiol (1985). 2004 May;96(5):1691-700. doi: 10.1152/japplphysiol.01054.2003. Epub 2004 Jan 5.
7
L-glutamine supplementation induces insulin resistance in adipose tissue and improves insulin signalling in liver and muscle of rats with diet-induced obesity.补充L-谷氨酰胺会诱导饮食诱导肥胖大鼠脂肪组织中的胰岛素抵抗，并改善其肝脏和肌肉中的胰岛素信号传导。
Diabetologia. 2007 Sep;50(9):1949-1959. doi: 10.1007/s00125-007-0723-z. Epub 2007 Jun 29.
8
Denervation and high-fat diet reduce insulin signaling in T-tubules in skeletal muscle of living mice.去神经支配和高脂饮食会降低活体小鼠骨骼肌横管中的胰岛素信号。
Diabetes. 2008 Jan;57(1):13-23. doi: 10.2337/db07-0516. Epub 2007 Oct 3.
9
Exercise training reduces insulin resistance and upregulates the mTOR/p70S6k pathway in cardiac muscle of diet-induced obesity rats.运动训练可降低饮食诱导肥胖大鼠心肌胰岛素抵抗并上调 mTOR/p70S6k 通路。
J Cell Physiol. 2011 Mar;226(3):666-74. doi: 10.1002/jcp.22387.
10
Restoration of skeletal muscle leptin response does not precede the exercise-induced recovery of insulin-stimulated glucose uptake in high-fat-fed rats.高脂喂养大鼠骨骼肌瘦素反应的恢复并不先于运动诱导的胰岛素刺激葡萄糖摄取的恢复。
Am J Physiol Regul Integr Comp Physiol. 2011 Feb;300(2):R492-500. doi: 10.1152/ajpregu.00602.2010. Epub 2010 Nov 17.
本文引用的文献
1
Chronic high fat feeding attenuates load-induced hypertrophy in mice.慢性高脂肪喂养可减弱小鼠因负荷引起的肥大。
J Physiol. 2009 Dec 1;587(Pt 23):5753-65. doi: 10.1113/jphysiol.2009.180174. Epub 2009 Oct 12.
2
Mechanisms linking obesity to insulin resistance and type 2 diabetes.将肥胖与胰岛素抵抗及2型糖尿病联系起来的机制。
Nature. 2006 Dec 14;444(7121):840-6. doi: 10.1038/nature05482.
3
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.IGF-1/PI3K/Akt信号通路通过抑制FOXO转录因子来阻止肌肉萎缩诱导的泛素连接酶的表达。
Mol Cell. 2004 May 7;14(3):395-403. doi: 10.1016/s1097-2765(04)00211-4.
4
Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta.Akt2/PKBβ基因敲除小鼠出现严重糖尿病、脂肪组织随年龄增长而减少以及轻度生长缺陷。
J Clin Invest. 2003 Jul;112(2):197-208. doi: 10.1172/JCI16885. Epub 2003 Jul 3.
5
Signalling pathways that mediate skeletal muscle hypertrophy and atrophy.介导骨骼肌肥大和萎缩的信号通路。
Nat Cell Biol. 2003 Feb;5(2):87-90. doi: 10.1038/ncb0203-87.
6
Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.PI(3)K/Akt/mTOR和PI(3)K/Akt/GSK3信号通路介导胰岛素样生长因子-1（IGF-1）诱导的骨骼肌肌管肥大
Nat Cell Biol. 2001 Nov;3(11):1009-13. doi: 10.1038/ncb1101-1009.
7
Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene.Akt1基因纯合缺失小鼠的生长发育迟缓及细胞凋亡增加。
Genes Dev. 2001 Sep 1;15(17):2203-8. doi: 10.1101/gad.913901.
8
Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice.Akt1/PKBα对小鼠的正常生长是必需的，但对维持葡萄糖稳态并非不可或缺。
J Biol Chem. 2001 Oct 19;276(42):38349-52. doi: 10.1074/jbc.C100462200. Epub 2001 Aug 31.
9
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta).缺乏蛋白激酶Akt2（PKBβ）的小鼠中的胰岛素抵抗和类糖尿病综合征
Science. 2001 Jun 1;292(5522):1728-31. doi: 10.1126/science.292.5522.1728.
10
Obesity and insulin resistance.肥胖与胰岛素抵抗。
J Clin Invest. 2000 Aug;106(4):473-81. doi: 10.1172/JCI10842.
Zotero 插件