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在婴儿期，使用甲状腺素和三碘甲状腺原氨酸联合治疗与肝血管瘤相关的消耗性甲状腺功能减退症。

Use of combined liothyronine and thyroxine therapy for consumptive hypothyroidism associated with hepatic haemangiomas in infancy.

机构信息

Department of Paediatric Endocrinology, Great Ormond Street Hospital and Institute for Child Health, London, UK.

出版信息

Horm Res Paediatr. 2010;74(2):149-52. doi: 10.1159/000281884. Epub 2010 Jun 3.

DOI:10.1159/000281884
PMID:20516650
Abstract

Hepatic haemiangiomas in infancy are rare. An association with hypothyroidism has been previously reported and is believed to be secondary to the conversion of thyroxine (fT4) to biologically inactive reverse triiodothyronine (rT3) by type 3 iodothyronine deiodinase (D3). We report a case that responded well to the combined use of liothyronine and thyroxine therapy.

摘要

婴儿期肝血管平滑肌脂肪瘤较为罕见。此前曾有报道称其与甲状腺功能减退症有关，据信这是由于 3 型甲状腺素脱碘酶（D3）将甲状腺素（fT4）转化为生物活性无的反式三碘甲状腺原氨酸（rT3）所致。我们报告了一例病例，该病例对左甲状腺素和甲状腺素联合治疗反应良好。

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