Department of Internal Medicine, Al Rashid Hospital, Kuwait.
Med Princ Pract. 2010;19(4):275-80. doi: 10.1159/000312713. Epub 2010 May 26.
The aims of the study were to compare obesity and its association with risk factors of atherosclerosis in Arabs and South Asians in Kuwait and to define which of the anthropometric parameters is best suited for clinical purposes in general.
Two hundred eighty adults, patients of Al-Rashid Hospital, a private general hospital in Kuwait, were enrolled in the study. Of the 280 patients, 144 were Arab and 136 were South Asian. Basic anthropometric parameters for obesity, fasting blood glucose, total cholesterol, low-density lipoprotein and high-density lipoprotein cholesterol and triglycerides (TG) were determined. The relationship between anthropometric variables and relevant metabolic variables, as well as a comparison between the different groups, was estimated using standard statistical methods.
Arabs were not only more obese [in males, p < 0.001 for body mass index (BMI), waist circumference (WC) and hip circumference (HC) and p = 0.001 for waist-to-hip ratio (WHR); in females, p < 0.001 for BMI, p = 0.004 for WC and p = 0.041 for HC], but also developed obesity at a younger age than did South Asians, even though, in South Asians, all anthropometric parameters were positively correlated with age (p = 0.004 for BMI, p = 0.001 for HC and p < 0.001 for WC and WHR). South Asians, however, were more prone to develop adverse effects in both lipid and glucose metabolism than Arabs were. In South Asian males, ethnicity was an independent predictor of triglycerides, according to the multiple linear regression analysis. The WHR appeared to be the most suitable predictor of dyslipidemia and impaired glucose metabolism.
The degree of adiposity was different between Arabs and South Asians in Kuwait. Abdominal obesity had a different impact on cardiovascular risk factors in these two ethnic groups in Kuwait.
本研究旨在比较科威特阿拉伯人和南亚人肥胖及其与动脉粥样硬化危险因素的关系，并确定哪种人体测量参数最适合一般临床用途。
本研究纳入了科威特一家私立综合医院 Al-Rashid 医院的 280 名成年患者。在这 280 名患者中，有 144 名是阿拉伯人，136 名是南亚人。测定了肥胖的基本人体测量参数、空腹血糖、总胆固醇、低密度脂蛋白和高密度脂蛋白胆固醇以及甘油三酯（TG）。使用标准统计方法评估了人体测量变量与相关代谢变量之间的关系，以及不同组之间的比较。
阿拉伯人不仅更肥胖[男性，体质指数（BMI）、腰围（WC）和臀围（HC）的 p<0.001，腰臀比（WHR）的 p=0.001；女性，BMI 的 p<0.001，WC 的 p=0.004，HC 的 p=0.041]，而且比南亚人更早出现肥胖，尽管南亚人的所有人体测量参数均与年龄呈正相关（BMI 的 p=0.004，HC 的 p=0.001，WC 的 p=0.041）。然而，南亚人比阿拉伯人更容易出现血脂和血糖代谢异常。在南亚男性中，根据多元线性回归分析，种族是甘油三酯的独立预测因子。WHR 似乎是血脂异常和糖代谢受损的最佳预测因子。
科威特的阿拉伯人和南亚人肥胖程度不同。腹部肥胖对这两个族群的心血管危险因素有不同的影响。
