Kim Daniel L, Osburn Leisha L, Cohen-Gadol Aaron A
Clarian Neuroscience, Indiana University, Indianapolis, IN 46202, USA.
Pediatr Neurosurg. 2010;46(1):71-5. doi: 10.1159/000315321. Epub 2010 Jun 1.
BACKGROUND/AIMS: Hemispherotomy has become a safe and effective surgical option for patients suffering from intractable epilepsy associated with diffuse unihemispheric malformations of cortical development. However, as compared to hemispherectomy, hemispherotomy, by leaving brain tissue behind, may leave some hemispheric connections intact, therefore increasing the risk of postoperative seizures. This is especially important to consider in the case of the highly epileptogenic hemisphere in hemimegalencephaly.
The authors use intraoperative electroencephalography (EEG) on the ipsilateral occipital lobe and contralateral hemisphere to confirm complete hemispheric disconnection during hemispherotomy surgery.
This technique has been successful in the confirmation of hemispheric disconnection as no patient has had recurrence of his/her seizure postoperatively.
Intraoperative EEG may be a useful tool to confirm hemispheric disconnection during hemispherotomy.
背景/目的:对于患有与弥漫性单侧半球皮质发育畸形相关的难治性癫痫患者,大脑半球切开术已成为一种安全有效的手术选择。然而,与大脑半球切除术相比,大脑半球切开术因保留了脑组织,可能会使一些半球连接保持完整,从而增加术后癫痫发作的风险。在半侧巨脑症中高度致痫的半球的情况下,这一点尤其需要考虑。
作者在大脑半球切开术期间使用同侧枕叶和对侧半球的术中脑电图(EEG)来确认半球完全离断。
该技术已成功用于确认半球离断,因为没有患者术后癫痫复发。
术中脑电图可能是在大脑半球切开术期间确认半球离断的有用工具。