Department of Psychiatry, University of Southampton, Southampton, UK.
Soc Psychiatry Psychiatr Epidemiol. 2011 Aug;46(8):703-10. doi: 10.1007/s00127-010-0237-8. Epub 2010 Jun 2.
A number of recent studies suggest that delusions may be explained as a continuum from normal beliefs. Fear of negative evaluation from others (FNE) is one of potential factors that might describe this psychological process of delusions.
In order to examine whether FNE is associated with delusional ideation in both non-clinical population and patients with schizophrenia, two sets of data [from a non-clinical student sample (n = 282) and from patients with schizophrenia (n = 117)] were collected to examine whether Brief Fear of Negative Evaluation Scale (BFNE) score and the 21-item Peters Delusions Inventory (PDI-21) score were associated with each other. Linear regression analyses were carried out to assess if the BFNE score still remained associated with the PDI-21 scores once the confounding effects of depression were controlled.
BFNE scores were significantly related to PDI-21 scores in both non-clinical [Pearson product-moment correlation coefficient (r) = 0.37, 95% confidence Interval (CI) = 0.25-0.48] and patient (r = 0.33, 95% CI = 0.14-0.49) samples. These associations were still significant when confounding effects of depression were controlled. Standardised coefficients for the BFNE scores in the linear regression model were 0.21 in the student sample and 0.19 in the clinical sample.
FNE was associated with delusional ideation both in non-clinical population and in patients with schizophrenia. FNE might be a potential target for both pharmacological and psychological interventions for patients with delusions.
多项近期研究表明,妄想可以被解释为正常信念的连续体。害怕他人的负面评价(FNE)是可能描述妄想这一心理过程的潜在因素之一。
为了检验 FNE 是否与非临床人群和精神分裂症患者的妄想观念有关,我们收集了两组数据[来自非临床学生样本(n=282)和精神分裂症患者(n=117)],以检验Brief Fear of Negative Evaluation Scale(BFNE)评分和 21 项 Peters 妄想量表(PDI-21)评分之间是否存在相关性。线性回归分析用于评估在控制抑郁的混杂效应后,BFNE 评分是否仍然与 PDI-21 评分相关。
在非临床[皮尔逊积矩相关系数(r)=0.37,95%置信区间(CI)=0.25-0.48]和患者(r=0.33,95%CI=0.14-0.49)样本中,BFNE 评分与 PDI-21 评分均显著相关。在控制抑郁的混杂效应后,这些相关性仍然显著。BFNE 评分在学生样本和临床样本中的线性回归模型中的标准化系数分别为 0.21 和 0.19。
FNE 与非临床人群和精神分裂症患者的妄想观念有关。FNE 可能是妄想患者药物和心理干预的潜在靶点。