1st Department of Medicine, Semmelweis University, H-1083 Budapest, Koranyi S 2A, Hungary.
World J Gastroenterol. 2010 Jun 7;16(21):2591-9. doi: 10.3748/wjg.v16.i21.2591.
During the course of the disease, most patients with Crohn's disease (CD) may eventually develop a stricturing or a perforating complication, and a significant number of patients with both CD and ulcerative colitis will undergo surgery. In recent years, research has focused on the determination of factors important in the prediction of disease course in inflammatory bowel diseases to improve stratification of patients, identify individual patient profiles, including clinical, laboratory and molecular markers, which hopefully will allow physicians to choose the most appropriate management in terms of therapy and intensity of follow-up. This review summarizes the available evidence on clinical, endoscopic variables and biomarkers in the prediction of short and long-term outcome in patients with inflammatory bowel diseases.
在疾病过程中，大多数克罗恩病（CD）患者最终可能会出现狭窄或穿孔并发症，而且相当数量的 CD 和溃疡性结肠炎患者将需要手术。近年来，研究的重点是确定炎症性肠病疾病过程预测中重要因素，以改善患者分层，确定包括临床、实验室和分子标志物在内的个体患者特征，这有望使医生能够根据治疗和随访强度选择最合适的管理方案。这篇综述总结了目前关于炎症性肠病患者短期和长期结局预测的临床、内镜变量和生物标志物的可用证据。
