盾叶薯蓣新鲜根茎中甾体皂苷的研究
[Research of steroidal saponins from the fresh rhizomes of Dioscorea zingiberensis].
作者信息
Yang Ru-Tong, Tong Hai-Ying
机构信息
Institute of botany, Jiangsu Province and Chinese Academy of Sciences, Nanjing 210014, China.
出版信息
Zhong Yao Cai. 2010 Jan;33(1):62-4.
OBJECTIVE
To study the steroidal saponins from the fresh rhizomes of Dioscorea zingiberensis and search for new bioactive compounds.
METHODS
The steroidal saponins were isolated by normal phase silica gel and RP-C18 column chromatography, their chemical structures were elucidated by MS and NMR methods.
RESULTS
One steroidal saponin was isolated from EtOH extract of the fresh rhizomes of D. zingiberensis and identified as 26-O-beta-D-glucopyranosyl-3beta, 22alpha, 26-trihydroxy-25(R)-furosta-5-en-3-O-[alpha-L-rhamnopyranosyl-(1 --> 4) ]-beta-D-glucopyranoside.
CONCLUSION
This compound is isolated from Dioscorea L. the first time.
目的
研究盾叶薯蓣新鲜根茎中的甾体皂苷，寻找新的生物活性化合物。
方法
采用正相硅胶柱色谱和RP-C18柱色谱分离甾体皂苷，通过质谱和核磁共振方法阐明其化学结构。
结果
从盾叶薯蓣新鲜根茎的乙醇提取物中分离得到一种甾体皂苷，鉴定为26-O-β-D-吡喃葡萄糖基-3β,22α,26-三羟基-25(R)-呋甾-5-烯-3-O-[α-L-鼠李吡喃糖基-(1→4)]-β-D-吡喃葡萄糖苷。
结论
该化合物首次从薯蓣属植物中分离得到。
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