Riboni Francesca, Giana Michele, Piantanida Paola, Vigone Alessandro, Surico Nicola, Boldorini Renzo
Unit of Obstetrics and Gynecology, Maggiore Hospital and University School of Medicine "Amedeo Avogadro," Novara, Italy.
Acta Cytol. 2010 May-Jun;54(3):311-3. doi: 10.1159/000325040.
Serous psammocarcinoma is a rare variant of epithelial neoplasia that can arise from the ovaries or peritoneum. It is characterized by massive psammoma body formation, invasiveness and low grade cytologic features.
A 70-year-old woman was admitted to our hospital; a bimanual examination with cervicovaginal smear was performed. The smears revealed neoplastic cells with psammoma bodies; afterward, endocervical curettage revealed microaggregates of epithelial neoplastic cells with psammoma bodies. Computed tomography of the abdomen showed a diffuse peritoneal carcinosis with left ovarian calcification. An exploratory laparotomy was carried out. Final pathologic findings showed peritoneal serous psammocarcinoma with ovarian implants.
Our report suggests that a Pap smear can play a role in the detection of peritoneal psammocarcinoma and underlines the significance of psammoma bodies as a cytologic marker of this rare tumor.
浆液性砂粒体癌是一种罕见的上皮性肿瘤变体，可起源于卵巢或腹膜。其特征为大量砂粒体形成、侵袭性及低级别细胞学特征。
一名70岁女性入院；进行了双合诊及宫颈阴道涂片检查。涂片显示有含砂粒体的肿瘤细胞；随后，宫颈管刮术显示有含砂粒体的上皮性肿瘤细胞微聚体。腹部计算机断层扫描显示弥漫性腹膜癌病伴左卵巢钙化。进行了剖腹探查术。最终病理结果显示为腹膜浆液性砂粒体癌伴卵巢种植。
我们的报告表明巴氏涂片可在腹膜砂粒体癌的检测中发挥作用，并强调了砂粒体作为这种罕见肿瘤的细胞学标志物的重要性。
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