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[腺肿大性噬血细胞性窦组织细胞增生症。1例的形态学和免疫学研究]

[Adenomegalic cytophagic sinusal histiocytosis. Morphological and immunologic study of a case].

作者信息

Nézelof C, Griscelli C, Jaubert F, Girot R

出版信息

Arch Fr Pediatr. 1978 Feb;35(2):118-29.

PMID:205185
Abstract

The case of a 14-year-old boy of North-African origin, presenting a phagocytic sinus histiocytosis is reported. The main features of this now classical disease are illustrated: its localization to the neck, its chronicity, the fact that it is well tolerated, the pseudotumoral appearance of the adenomegaly as well as the intensive phagocytic (essentially lymphocytophagic) activity of the sinus macrophages. The bringing to light in a picture of hyperimmunity of an elevated percentage of antibodies against the measles and EB viruses, associated with a temporary depression of the cellular immunity, suggest that this lymphophagocytosis could be controlled and facilitated by preferential opsonization of lymphoid cells carrying on their membrane the antigen of the virus or viruses initially responsible.

摘要

报告了一例14岁北非裔男孩患吞噬性窦组织细胞增多症的病例。阐述了这种现已成为经典疾病的主要特征:其病变位于颈部、病程呈慢性、耐受性良好、淋巴结肿大呈假瘤样外观以及窦巨噬细胞具有强烈的吞噬活性(主要为淋巴细胞吞噬活性)。在高免疫状态下发现针对麻疹病毒和EB病毒的抗体百分比升高,同时伴有细胞免疫的暂时抑制,这表明这种淋巴细胞吞噬作用可能通过优先调理作用于携带最初致病病毒抗原的淋巴细胞而得到控制和促进。

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1
[Adenomegalic cytophagic sinusal histiocytosis. Morphological and immunologic study of a case].[腺肿大性噬血细胞性窦组织细胞增生症。1例的形态学和免疫学研究]
Arch Fr Pediatr. 1978 Feb;35(2):118-29.
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