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Unraveling the roles of WRN and DNA-PKcs at telomeres.

作者信息

Beattie Tara L, Lees-Miller Susan P

机构信息

Department of Biochemistry, The Southern Alberta Cancer Research Institute, University of Calgary, AB, Canada.

出版信息

Aging (Albany NY). 2010 May;2(5):257-8. doi: 10.18632/aging.100150.

Abstract
摘要

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本文引用的文献

1
Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops.
Aging (Albany NY). 2010 May;2(5):274-84. doi: 10.18632/aging.100141.
2
Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase.
Nucleic Acids Res. 2010 Jul;38(12):3984-98. doi: 10.1093/nar/gkq144. Epub 2010 Mar 9.
3
Telomeres: protecting chromosomes against genome instability.
Nat Rev Mol Cell Biol. 2010 Mar;11(3):171-81. doi: 10.1038/nrm2848. Epub 2010 Feb 3.
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Roles of Werner syndrome protein in protection of genome integrity.
DNA Repair (Amst). 2010 Mar 2;9(3):331-44. doi: 10.1016/j.dnarep.2009.12.011. Epub 2010 Jan 13.
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DNA-PK: the means to justify the ends?
Adv Immunol. 2008;99:33-58. doi: 10.1016/S0065-2776(08)00602-0.
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How shelterin protects mammalian telomeres.
Annu Rev Genet. 2008;42:301-34. doi: 10.1146/annurev.genet.41.110306.130350.
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Shelterin: the protein complex that shapes and safeguards human telomeres.
Genes Dev. 2005 Sep 15;19(18):2100-10. doi: 10.1101/gad.1346005.
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Telomere biology: integrating chromosomal end protection with DNA damage response.
Chromosoma. 2005 Sep;114(4):275-85. doi: 10.1007/s00412-005-0338-4. Epub 2005 Oct 15.
10
Erosion of the telomeric single-strand overhang at replicative senescence.
Nat Genet. 2003 Apr;33(4):492-6. doi: 10.1038/ng1127. Epub 2003 Mar 24.

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