穿透性角膜移植术治疗活跃性棘阿米巴角膜炎。
Penetrating keratoplasty in active Acanthamoeba keratitis.
机构信息
Department of Ophthalmology, SUNY Upstate Medical University, Syracuse, NY 13202, USA.
出版信息
Cornea. 2010 Sep;29(9):1000-4. doi: 10.1097/ICO.0b013e3181cc79a1.
PURPOSE
To report the results of penetrating keratoplasty (PK) in active Acanthamoeba keratitis (AK).
METHODS
Nine patients with deep stromal infiltrates because of AK were treated with intensive antiamoebic medical therapy followed by PK during the acute infectious phase because of poor clinical response or poor compliance. Antiamoebic therapy was tapered after PK.
RESULTS
Visual acuity ranged from 20/15 to 20/50 after an average of 17 months after PK with no signs of recurrences. Patients had rapid resolution of symptoms.
CONCLUSION
PK is a viable option for active AK not responding to maximum medical treatment.
目的
报告穿透性角膜移植术（PK）治疗活跃棘阿米巴角膜炎（AK）的结果。
方法
9 例因 AK 导致深层基质浸润的患者，由于临床反应不佳或不遵医嘱，在急性感染期接受强化抗阿米巴药物治疗后，行 PK 治疗。PK 后抗阿米巴药物治疗逐渐减少。
结果
平均 17 个月后行 PK，视力从 20/15 到 20/50，无复发迹象。患者症状迅速缓解。
结论
对于对抗阿米巴药物治疗无反应的活跃 AK，PK 是一种可行的选择。
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