Department of Paediatrics, College of Medicine, Blantyre, Malawi.
PLoS Med. 2010 May 25;7(5):e1000273. doi: 10.1371/journal.pmed.1000273.
Although 80% of children with disabilities live in developing countries, there are few culturally appropriate developmental assessment tools available for these settings. Often tools from the West provide misleading findings in different cultural settings, where some items are unfamiliar and reference values are different from those of Western populations.
Following preliminary and qualitative studies, we produced a draft developmental assessment tool with 162 items in four domains of development. After face and content validity testing and piloting, we expanded the draft tool to 185 items. We then assessed 1,426 normal rural children aged 0-6 y from rural Malawi and derived age-standardized norms for all items. We examined performance of items using logistic regression and reliability using kappa statistics. We then considered all items at a consensus meeting and removed those performing badly and those that were unnecessary or difficult to administer, leaving 136 items in the final Malawi Developmental Assessment Tool (MDAT). We validated the tool by comparing age-matched normal children with those with malnutrition (120) and neurodisabilities (80). Reliability was good for items remaining with 94%-100% of items scoring kappas >0.4 for interobserver immediate, delayed, and intra-observer testing. We demonstrated significant differences in overall mean scores (and individual domain scores) for children with neurodisabilities (35 versus 99 [p<0.001]) when compared to normal children. Using a pass/fail technique similar to the Denver II, 3% of children with neurodisabilities passed in comparison to 82% of normal children, demonstrating good sensitivity (97%) and specificity (82%). Overall mean scores of children with malnutrition (weight for height <80%) were also significantly different from scores of normal controls (62.5 versus 77.4 [p<0.001]); scores in the separate domains, excluding social development, also differed between malnourished children and controls. In terms of pass/fail, 28% of malnourished children versus 94% of controls passed the test overall.
A culturally relevant developmental assessment tool, the MDAT, has been created for use in African settings and shows good reliability, validity, and sensitivity for identification of children with neurodisabilities.
尽管 80%的残疾儿童生活在发展中国家,但这些国家缺乏适合文化的发展评估工具。在不同的文化背景下,西方的工具往往会提供误导性的发现,因为其中一些项目不熟悉,参考值也与西方人群不同。
在初步和定性研究之后,我们制作了一个包含 162 个项目的发展评估工具草稿,涵盖四个发展领域。经过面部和内容有效性测试和试点,我们将草稿工具扩展到 185 个项目。然后,我们评估了来自马拉维农村的 1426 名正常农村儿童(0-6 岁),并为所有项目得出了年龄标准化的规范。我们使用逻辑回归检查项目的表现,并使用kappa 统计检查可靠性。然后,我们在共识会议上考虑所有项目,删除表现不佳和不必要或难以管理的项目,最后在马拉维发展评估工具(MDAT)中留下 136 个项目。我们通过将年龄匹配的正常儿童与营养不良(120 名)和神经发育障碍(80 名)儿童进行比较来验证该工具。对于其余项目,观察者间即时、延迟和观察者内测试的kappa 值>0.4 的项目比例为 94%-100%,可靠性良好。与正常儿童相比,神经发育障碍儿童的总平均分(和各领域得分)差异显著(35 与 99 [p<0.001])。使用类似于丹佛二氏的通过/失败技术,3%的神经发育障碍儿童通过,而 82%的正常儿童通过,表明敏感性(97%)和特异性(82%)良好。与正常对照组相比,营养不良儿童(身高体重<80%)的总平均分也明显不同(62.5 与 77.4 [p<0.001]);营养不良儿童和对照组在社会发展除外的各领域得分也不同。在通过/失败方面,28%的营养不良儿童与 94%的对照组儿童总体上通过了测试。
为非洲环境创建了一个文化相关的发展评估工具 MDAT,它具有良好的可靠性、有效性和敏感性,可用于识别神经发育障碍儿童。