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使用蛋白质组学PatternLab分析鸟枪法蛋白质组学数据。

Analyzing shotgun proteomic data with PatternLab for proteomics.

作者信息

Carvalho Paulo C, Yates Iii John R, Barbosa Valmir C

机构信息

Systems Engineering and Computer Science Program, COPPE, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

The Scripps Research Institute, La Jolla, California.

出版信息

Curr Protoc Bioinformatics. 2010 Jun;Chapter 13:13.13.1-13.13.15. doi: 10.1002/0471250953.bi1313s30.

DOI:10.1002/0471250953.bi1313s30
PMID:20521246
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2933420/
Abstract

PatternLab for proteomics is a one-stop shop computational environment for analyzing shotgun proteomic data. Its modules provide means to pinpoint proteins/peptides that are differentially expressed and those that are unique to a state. It can also cluster the ones that share similar expression profiles in time-course experiments, as well as help in interpreting results according to Gene Ontology. PatternLab is user-friendly, simple, and provides a graphical user interface.

摘要

蛋白质组学模式实验室是一个用于分析鸟枪法蛋白质组学数据的一站式计算环境。其模块提供了确定差异表达的蛋白质/肽段以及特定状态下独特蛋白质/肽段的方法。它还可以在时间进程实验中对具有相似表达谱的蛋白质/肽段进行聚类，以及根据基因本体论帮助解释结果。模式实验室用户友好、操作简单，并提供图形用户界面。

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