Department of Child Health, Division of Developmental Medicine, University of Glasgow, Glasgow, UK.
Arch Dis Child. 2010 Aug;95(8):612-7. doi: 10.1136/adc.2009.164491. Epub 2010 Jun 3.
To explore how fat, lean and body mass index (BMI) track in childhood and how this relates to parental obesity.
Prospective population-based cohort study: Avon Longitudinal Study of Parents and Children, UK.
Height, weight and leg-to-leg bioelectrical impedance (BIA) were collected at ages 7 and 11 years, as well as pre-pregnancy parental heights and weights. For BMI International Obesity Task Force thresholds of obesity and overweight were used. Impedance data were expressed as separate lean and fat z scores, internally standardised for gender, height and age and a child was defined as over-fat if fat z score was >85th and very over-fat if >95th internal centile.
Data were available for 7723 and 7252 children at ages 7 and 11 years, respectively (6066 at both time points). Of those obese at age 7, 75% were still obese at age 11, while of those who had been overweight 16% had become obese and 20% now had normal BMI. Both fat and lean z scores showed moderate levels of tracking (correlation coefficients 0.70 and 0.73, respectively). Children with one or two obese parents had higher fat z scores at age 7 and showed greater increases in fat thereafter. They were more likely to be very over-fat at age 7 and, of these, 69% remained so at age 11 compared to only 45% with non-obese parents (p <0.001).
Children of obese parents already have high fat levels at age 7 and are more likely to remain very over-fat.
探讨儿童时期脂肪、瘦体重和体重指数（BMI）的变化轨迹，以及这与父母肥胖的关系。
前瞻性基于人群的队列研究：英国阿冯纵向研究父母与子女。
在 7 岁和 11 岁时测量身高、体重和腿部-腿部生物电阻抗（BIA），并收集父母在怀孕前的身高和体重。使用国际肥胖工作组 BMI 肥胖和超重的阈值。将阻抗数据表示为单独的瘦体重和脂肪 z 分数，根据性别、身高和年龄进行内部标准化，并且如果脂肪 z 分数> 85 百分位，则定义儿童为超重，如果脂肪 z 分数> 95 百分位，则定义为非常超重。
分别在 7 岁和 11 岁时获得了 7723 名和 7252 名儿童的数据（两个时间点均有 6066 名儿童）。在 7 岁时肥胖的儿童中，75%在 11 岁时仍肥胖，而在超重的儿童中，16%已变为肥胖，20%现在 BMI 正常。脂肪和瘦体重 z 分数均显示出中度的跟踪（相关系数分别为 0.70 和 0.73）。有一个或两个肥胖父母的儿童在 7 岁时的脂肪 z 分数较高，此后脂肪增加幅度更大。他们在 7 岁时更有可能是非常超重，其中 69%在 11 岁时仍然如此，而父母不肥胖的儿童只有 45%（p<0.001）。
肥胖父母的孩子在 7 岁时已经有较高的脂肪水平，并且更有可能保持非常超重。
