Su Yuantao, Suhaimi Marini Ahmad, Gupta Manish Prasad, Du Wenchong, Hua Jing
Department of Women's and Children's Health Care, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
NTU Psychology, School of Social Sciences, Nottingham Trent University, UK.
Obes Rev. 2025 Sep;26(9):e13939. doi: 10.1111/obr.13939. Epub 2025 May 10.
Existing evidence shows inconsistent associations between preterm birth and childhood obesity. The impact of full gestational age on the risk of childhood obesity and overweight remains unclear.
This systematic scoping review aims to comprehensively explore the relationship between gestational age at birth across the entire spectrum and childhood overweight and obesity.
A thorough search of online databases (PubMed, Ovid Medline, and Google Scholar) covering the period from January 2000 to September 2024 was conducted using selected keyword strings following the PRISMA-SCR guidelines. Studies investigating childhood overweight or obesity as either a primary or secondary outcome in association with various degrees of births were included.
Twenty-eight studies met the inclusion criteria. Substantial evidence linked preterm births to childhood overweight/obesity. However, the available evidence for term-born and post-term-born children was limited, showing mixed results regarding their relationship with childhood overweight and obesity.
The available evidence regarding the association between different gestational age categories and childhood overweight/obesity is limited. This review underscores the importance of implementing primary prevention strategies during early childhood and highlights the need for further research to enhance our understanding of the nuanced relationship between gestational age and childhood overweight/obesity.
现有证据表明早产与儿童肥胖之间的关联并不一致。足月儿对儿童肥胖和超重风险的影响仍不明确。
本系统综述旨在全面探讨全孕周范围内的出生孕周与儿童超重和肥胖之间的关系。
按照PRISMA-SCR指南，使用选定的关键词组对2000年1月至2024年9月期间的在线数据库（PubMed、Ovid Medline和谷歌学术）进行全面检索。纳入将儿童超重或肥胖作为与不同程度出生相关的主要或次要结局进行研究的文献。
28项研究符合纳入标准。大量证据表明早产与儿童超重/肥胖有关。然而，关于足月儿和过期产儿的现有证据有限，显示出它们与儿童超重和肥胖关系的结果不一。
关于不同孕周类别与儿童超重/肥胖之间关联的现有证据有限。本综述强调了在幼儿期实施一级预防策略的重要性，并突出了进一步研究以增进我们对孕周与儿童超重/肥胖之间细微关系理解的必要性。
