Petitto V B, Buckley E G
Duke University Eye Center, Duke University Medical Center, Durham, NC 27710.
Ophthalmology. 1991 Apr;98(4):509-12; discussion 512-3. doi: 10.1016/s0161-6420(91)32264-4.
Botulinum toxin was used to treat 20 patients with strabismus after retinal detachment surgery. Preinjection motility deviations ranged from 10 to 60 prism diopters (D). Postinjection deviations ranged from 0 to 20 prism D, with 75% being 10 D or less. Eighty-five percent achieved fusion that persisted, with 73% requiring only one or two injections. Only muscles in the eye that had undergone retinal reattachment surgery were injected. The average period of follow-up was 12 months. Complications were rare and all resolved spontaneously. Botulinum toxin appears to be useful as a primary treatment modality for persistent strabismus following retinal detachment surgery, possibly obviating the need for complicated strabismus surgery.
肉毒杆菌毒素被用于治疗20例视网膜脱离手术后斜视的患者。注射前的运动偏差范围为10至60棱镜度（D）。注射后的偏差范围为0至20棱镜度D，其中75%为10棱镜度或更小。85%的患者实现了持续融合，73%的患者仅需注射一两次。仅对接受视网膜复位手术的眼睛的肌肉进行注射。平均随访期为12个月。并发症罕见，且均自行缓解。肉毒杆菌毒素似乎可作为视网膜脱离手术后持续性斜视的主要治疗方式，可能无需进行复杂的斜视手术。
