Lee J, Page B, Lipton J
Toxin Clinic, Moorfields Eye Hospital, London.
Eye (Lond). 1991;5 ( Pt 4):451-5. doi: 10.1038/eye.1991.73.
Thirty-one consecutive patients were treated with injections of Botulinum Neurotoxin A to rectus muscles for strabismus following retinal detachment surgery. In 14 cases the presenting problem was diplopia and in 17 cases the presenting problem was cosmetic appearance. A total of 67 injections was given. Twenty-seven cases had nine months or more follow-up. Of these, four of 11 cases with diplopia had fusion restored, four were shown to have no fusion potential, and three had temporary improvement only. In 16 cases with a primary cosmetic problem there was no useful effect in two, three had surgery as an alternative, three were realigned long-term, and eight had continuing maintenance therapy with toxin. Over half the series had undergone multiple detachment surgery, often for giant tears and other complex pathology.
31例视网膜脱离手术后因斜视接受肉毒杆菌神经毒素A注射至直肌治疗的连续患者。14例主要问题为复视，17例主要问题为外观。共进行了67次注射。27例患者随访9个月或更长时间。其中，11例复视患者中有4例恢复了融合功能，4例显示无融合潜能，3例仅暂时改善。16例主要存在外观问题的患者中，2例无效，3例选择手术作为替代方案，3例长期重新对齐，8例继续接受毒素维持治疗。超过半数的患者接受过多次视网膜脱离手术，通常是针对巨大裂孔和其他复杂病变。
