Khan Khalid, Qureshi Ahmed Nadeem, Bibi Phool, Jehanzeb Muhammad
Department of Radiology, Ayub Medical College, Abbottabad, Pakistan.
J Ayub Med Coll Abbottabad. 2009 Apr-Jun;21(2):42-4.
CT scan has replaced most of the invasive techniques in diagnosis of brain tumours because it can accurately demonstrate, localize and characterize the brain tumours. The objective of this study was to observe the accuracy of CT scan in the diagnosis of brain tumours in children by comparing it with histopathology. This descriptive case series was conducted at Department of Radiology, Ayub Teaching Hospital Abbottabad from 10th March 2005 to 9th March 2007.
Both pre and post contrast CT scan was carried out on 120 patients referred to Radiology Department for CT scan suspected of having brain tumours. Data of CT findings/diagnosis of patients having brain tumours were collected on a proforma. Histopathology of specimen from operation or biopsy was carried out and compared with the CT scan diagnosis.
Glial tumours comprised the largest category 68 (56.67%). Medulloblastoma was 23 (19.16%) Craniopharyngioma 8 (6.63%) and Ependymoma were 6 (5.09%) each. Hemangioblastoma 2 (1.67%), Choroid plexus one (0.83%) adenoma and pineal tumours were 9 (3.33%) each. As regards comparison between CT and histopathology, an agreement between the two was found in 104 (86.67%) cases whereas in 16 (13.33%) of the cases, the histopathology reports were different. In case of Astrocytomas 63 (92.64%) were confirmed on histopathology and 5 (7.36%) was reported differently. In Medulloblastomas 19 (82.60%) were accurately diagnosed on CT scan. Sensitivity of CT scan in diagnosis of brain tumours in children was 93.33%.
CT Scan is more accurate predictor of brain tumour yet it is not always 100% accurate.
CT扫描已取代了大多数用于诊断脑肿瘤的侵入性技术，因为它能够准确地显示、定位并描述脑肿瘤的特征。本研究的目的是通过与组织病理学结果进行比较，观察CT扫描在诊断儿童脑肿瘤方面的准确性。本描述性病例系列研究于2005年3月10日至2007年3月9日在阿伯塔巴德阿尤布教学医院放射科开展。
对120名因疑似患有脑肿瘤而被转至放射科进行CT扫描的患者进行了平扫及增强CT扫描。在一份表格上收集了患有脑肿瘤患者的CT检查结果/诊断数据。对手术或活检标本进行了组织病理学检查，并与CT扫描诊断结果进行比较。
胶质细胞瘤占比最大，为68例（56.67%）。髓母细胞瘤23例（19.16%），颅咽管瘤8例（6.63%），室管膜瘤各6例（5.09%）。血管母细胞瘤2例（1.67%），脉络丛腺瘤1例（0.83%），松果体肿瘤各9例（3.33%）。至于CT与组织病理学的比较，二者结果相符的有104例（86.67%），而在16例（13.33%）病例中，组织病理学报告结果不同。在星形细胞瘤病例中，63例（92.64%）经组织病理学确诊，5例（7.36%）报告结果不同。在髓母细胞瘤病例中，19例（82.60%）经CT扫描准确诊断。CT扫描对儿童脑肿瘤诊断的敏感性为93.33%。
CT扫描是脑肿瘤更准确的预测指标，但并不总是100%准确。
