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癫痫患者中抑郁症的发病率:一项基于医院的研究。

Frequency of depression in epilepsy: a hospital based study.

作者信息

Yousafzai Aziz-ur-Rehman, Yousafzai Abdul Wahab, Taj Rizwan

机构信息

Department of Psychiatry, Ayub Medical College, Abbottabad, Pakistan.

出版信息

J Ayub Med Coll Abbottabad. 2009 Apr-Jun;21(2):73-5.

Abstract

BACKGROUND

Depression is the most frequent psychiatric morbidity among epileptic patients adversely affecting their quality of life. It has also been associated with deliberate self harm and suicide. The objectives of this study were to know the frequency of depression in epileptic patients coming to neurology clinic of tertiary care hospital and also to find an association of clinical and demographic variables of epileptic patients with depression.

METHODS

Convenient sampling method was used to select patients after informed consent. Depression was diagnosed using semi structured interview based on ICD-10. Data was analyses using SPSS version 10.0, and analysis carried out using descriptive and inferential statistics. Chi-square test of association was applied to see the significance.

RESULT

Out of total 100 patients 55% were males, 47% were married and mean age of the patients was 25.5 +/- 4.34 years. About 60% patients were found depressed at the time of interview. Male patients, being married and coming from low socioeconomic stratum were significantly associated with depression. None of the patient was on anti-depressant medication.

CONCLUSION

Depression was found to be highly prevalent psychiatric morbidity in epileptic patients. Men, married status, uncontrolled epilepsy and low socioeconomic group more prone to have depression.

摘要

背景

抑郁症是癫痫患者中最常见的精神疾病,对他们的生活质量产生不利影响。它还与蓄意自残和自杀有关。本研究的目的是了解到三级护理医院神经科门诊就诊的癫痫患者中抑郁症的发生率,并找出癫痫患者的临床和人口统计学变量与抑郁症之间的关联。

方法

采用方便抽样法在患者签署知情同意书后选取患者。根据国际疾病分类第10版(ICD - 10),通过半结构化访谈诊断抑郁症。使用SPSS 10.0版软件进行数据分析,并运用描述性和推断性统计方法进行分析。应用卡方关联检验来观察其显著性。

结果

在总共100名患者中,55%为男性,47%已婚,患者的平均年龄为25.5 +/- 4.34岁。在访谈时发现约60%的患者患有抑郁症。男性患者、已婚以及来自社会经济地位较低阶层与抑郁症显著相关。没有患者正在服用抗抑郁药物。

结论

抑郁症在癫痫患者中是一种高度普遍的精神疾病。男性、已婚状况、癫痫未得到控制以及社会经济地位较低的群体更容易患抑郁症。

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