Dermatology, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
J Dermatolog Treat. 2011 Feb;22(1):49-51. doi: 10.3109/09546630903440072. Epub 2010 Jun 5.
Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare and benign disease characterized by red to brown papules or nodules primarily in the head and neck region. Different treatment modalities including surgical excision, cryotherapy, chemotherapy, intralesional and systemic corticosteroids, curettage, electrodesiccation, radiation, and carbon dioxide, argon and pulsed dye lasers have been used with limited success; recurrences are common.
We report a case of refractory ALHE who was successfully treated by surgery after several unsuccessful attempts with other conventional therapies.
We believe, in refractory cases of ALHE, surgery is still the logical and optimum treatment with fewer recurrences in the long term.
血管淋巴样增生伴嗜酸性粒细胞增多症（ALHE）是一种罕见的良性疾病，以头颈部的红色至棕色丘疹或结节为特征。不同的治疗方法包括手术切除、冷冻疗法、化疗、局部和全身皮质类固醇、刮除术、电干燥术、放射治疗和二氧化碳、氩气和脉冲染料激光等，均取得了一定的疗效，但复发率较高。
我们报告了一例难治性 ALHE 患者，在多次尝试其他常规治疗方法失败后，手术治疗获得成功。
我们认为，对于难治性 ALHE 病例，手术仍然是合理且最佳的治疗方法，长期来看复发率较低。
