非免疫球蛋白 E 介导的食物免疫反应。
Nonimmunoglobulin e-mediated immune reactions to foods.
机构信息
Assistant Professor of Pediatrics, Division of Allergy and Immunology, Department of Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
出版信息
Allergy Asthma Clin Immunol. 2006 Jun 15;2(2):78-85. doi: 10.1186/1710-1492-2-2-78.
: Adverse food reactions are abnormal responses to ingested foods. Reactions vary from immunologic to nonimmunologic immune reactions and can be either immunoglobulin E (IgE) mediated or non-IgE mediated. Food-induced IgE-mediated reactions range from localized urticaria to anaphylaxis and have been well studied. However, in comparison, there has been significantly less research into non-IgE-mediated food reactions. Non-IgE-mediated reactions can cause respiratory, gastrointestinal, and cutaneous symptoms. The most recent evidence suggests that these reactions are probably T-cell mediated as evidenced in lymphocyte proliferation assays. This review will explore the symptoms and testing methods of the most common non-IgE-mediated reactions.
食物不良反应是对摄入食物的异常反应。反应从免疫到非免疫免疫反应不等，并且可以是免疫球蛋白 E（IgE）介导的或非 IgE 介导的。食物诱导的 IgE 介导的反应范围从局部荨麻疹到过敏反应，并且已经得到了很好的研究。然而，相比之下，对于非 IgE 介导的食物反应的研究要少得多。非 IgE 介导的反应可引起呼吸、胃肠道和皮肤症状。最近的证据表明，这些反应可能是 T 细胞介导的，如淋巴细胞增殖试验所示。本综述将探讨最常见的非 IgE 介导的反应的症状和测试方法。
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