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口腔扁平苔藓:对110例巴西患者的回顾性研究。

Oral lichen planus: A retrospective study of 110 Brazilian patients.

作者信息

Oliveira Alves Mônica Ghislaine, Almeida Janete Dias, Balducci Ivan, Guimarães Cabral Luiz Antonio

机构信息

Department of Biosciences and Oral Diagnosis, São José dos Campos Dental School, São Paulo State University, São José dos Campos, São Paulo, Brazil.

出版信息

BMC Res Notes. 2010 Jun 3;3:157. doi: 10.1186/1756-0500-3-157.

Abstract

BACKGROUND

Oral lichen planus (OLP) is a chronic autoimmune disease characterized by multiple clinical presentations and a relatively high prevalence in the population. This retrospective patient record study investigated the profile of OLP in a group of Brazilian patients seen between 1989 and 2009.

FINDINGS

The clinical records were analyzed and data such as gender, age, race, clinical presentation of OLP, site affected, presence of symptoms and extraoral manifestations of the disease, smoking habit, and consumption of alcoholic beverages were obtained. Among the 1822 records of patients with oral mucosal lesions, OLP was identified in 6.03%. Of these, 76.36% were females, with a mean age of 54 years, and 85% were whites. The reticular form was the most frequent (81.81%). Extraoral lesions were observed in 32.72% of the patients and painful symptoms were reported by 50.90%. The cheek mucosa was the site most affected (92.72%) and multiple oral lesions were observed in 77.27% of the patients. Among patients with OLP, 18.18% reported a smoking habit and 29.09% the consumption of alcoholic beverages.

CONCLUSIONS

This retrospective study showed a relatively high prevalence of OLP in the population studied, with a predominance of the disease among middle-aged white women and bilateral involvement of the cheek mucosa. Reticular lesions were the most frequent, followed by the erosive form which is mainly associated with painful symptoms. No relationship with tobacco or alcohol consumption was observed.

摘要

背景

口腔扁平苔藓(OLP)是一种慢性自身免疫性疾病,具有多种临床表现,在人群中的患病率相对较高。这项回顾性患者记录研究调查了1989年至2009年间一组巴西患者的OLP情况。

研究结果

对临床记录进行了分析,获取了性别、年龄、种族、OLP的临床表现、受累部位、症状的存在情况以及该疾病的口外表现、吸烟习惯和酒精饮料消费等数据。在1822份口腔黏膜病变患者的记录中,OLP的确诊率为6.03%。其中,76.36%为女性,平均年龄为54岁,85%为白人。网状型最为常见(81.81%)。32.72%的患者观察到口外病变,50.90%的患者报告有疼痛症状。颊黏膜是最常受累的部位(92.72%),77.27%的患者观察到多个口腔病变。在OLP患者中,18.18%报告有吸烟习惯,29.09%报告有酒精饮料消费。

结论

这项回顾性研究表明,在所研究的人群中OLP的患病率相对较高,该疾病在中年白人女性中占主导,且颊黏膜双侧受累。网状病变最为常见,其次是糜烂型,主要与疼痛症状相关。未观察到与烟草或酒精消费的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7152/2898663/112eae55d600/1756-0500-3-157-1.jpg

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