Radochová Vladimíra, Dřízhal Ivo, Slezák Radovan
M.D, Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Dentistry.
M.D, PhD, Assoc. Prof, Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic: Department of Dentistry.
J Clin Exp Dent. 2014 Dec 1;6(5):e556-61. doi: 10.4317/jced.51784. eCollection 2014 Dec.
Oral lichen planus is chronic inflammatory disease with a high prevalence in the population. This study describes the epidemiological and clinical characteristics of group of patients with oral lichen planus in the Czech Republic.
Data was taken from the medical records of 171 patients referred to the Oral Medicine Unit at the University Hospital in Hradec Králové with histologically confirmed clinical diagnosis of oral lichen planus in the period 2003 - 2013. The data were retrospectively reviewed.
Of the 171 patients, 116 (67.8%) were women and 55 (32.2%) were men. The mean age was 55.2 ± 12.4 years (range of 85.0 - 20.9). The reticular form was the most frequent 93.6% (160 pts.), desquamative gingivitis was 12.9% (22). The buccal mucosa was the site most affected 89.5% (153 pts.). The lesions were asymptomatic in 52 patients (30.4%). Extraoral lesions were observed in 20.5% (35 pts.) of the patients, skin involvement was in 16.4% (28 pts.). Smokers were 29 patients. Local treatment used 116 (67.8%), only 6 patients used systemic short tome corticoid therapy. No evidence between OLP and malignant transformation was observed.
This retrospective study show very similar profile and clinical features of the patients with OLP as in other studies. Key words:Oral lichen planus, clinical features, extraoral manifestation.
口腔扁平苔藓是一种在人群中患病率较高的慢性炎症性疾病。本研究描述了捷克共和国一组口腔扁平苔藓患者的流行病学和临床特征。
数据取自2003年至2013年期间转诊至赫拉德茨克拉洛韦大学医院口腔医学科的171例患者的病历,这些患者经组织学确诊为口腔扁平苔藓。对数据进行回顾性分析。
171例患者中,女性116例(67.8%),男性55例(32.2%)。平均年龄为55.2±12.4岁(范围为85.0 - 20.9岁)。网状型最为常见,占93.6%(160例),剥脱性龈炎占12.9%(22例)。颊黏膜是最常受累的部位,占89.5%(153例)。52例患者(30.4%)的病变无症状。20.5%(35例)的患者有口腔外病变,16.4%(28例)有皮肤受累。吸烟者有29例。116例(67.8%)采用局部治疗,仅6例患者采用全身性短期皮质类固醇治疗。未观察到口腔扁平苔藓与恶变之间的关联。
这项回顾性研究显示,口腔扁平苔藓患者的特征和临床特征与其他研究非常相似。关键词:口腔扁平苔藓;临床特征;口腔外表现