Ślebioda Zuzanna, Drożdżyńska Julia, Karpińska Aleksandra, Krzyżaniak Aleksandra, Kasperczak Marianna, Tomoń Natalia, Wiśniewska Paulina, Wyganowska Marzena Liliana
Department of Dental Surgery, Periodontology and Oral Mucosa Diseases, Poznan University of Medical Sciences, 70 Bukowska St., 60-812 Poznań, Poland.
Medical Faculty, Poznan University of Medical Sciences, 60-812 Poznań, Poland.
J Clin Med. 2024 Dec 3;13(23):7363. doi: 10.3390/jcm13237363.
Lichen planus (LP) is a chronic, recurrent mucocutaneous inflammatory disease that develops due to a disturbed immunological response triggered by endogenous and exogenous factors. To evaluate clinical presentation, demographic characteristics, and risk factors in a cohort of Polish patients with oral lichen planus (OLP). Medical records of 186 patients with OLP referred to the student outpatient clinic in Poznań University of Medical Sciences from 2013 to 2023 were analyzed in order to establish clinical presentation, patient's demographic characteristics, and risk factors for OLP. We considered data regarding age, sex, medical history, habits, subjective complaints, clinical type, localization, histology, and treatment. Patients with OLP constituted 20.1% of 887 admitted patients. Of the 186 patients with OLP, 130 (69.9%) were females and 56 (30.1%) were males. The average age at the diagnosis was 60.7 years (range 15-95 years). Only 24.2% of patients reported smoking. The most common intraoral presentation of OLP was reticular form (61.8%), followed by mixed erosive-bullous type (15%), and atrophic (6.4%). Pathologic lesions were most commonly located on buccal mucosa (89.2%) and tongue (58.6%). Subjective complaints included pain (48.4%), burning sensation (46.2%), xerostomia (25.3%), bleeding (10.2%), taste disturbance (4.8%), and excessive saliva production (3.8%), while 22.6% of OLP patients were asymptomatic. The most common type of OLP in Polish patients was reticular, developing mostly on the buccal mucosa and tongue. It was found most often in non-smoking middle-aged women. Subjective complaints were reported by over 77% of patients.
扁平苔藓（LP）是一种慢性复发性黏膜皮肤炎症性疾病，由内源性和外源性因素触发的免疫反应紊乱所致。为评估一组波兰口腔扁平苔藓（OLP）患者的临床表现、人口统计学特征及危险因素。分析了2013年至2023年转诊至波兹南医科大学学生门诊的186例OLP患者的病历，以确定OLP的临床表现、患者人口统计学特征及危险因素。我们考虑了有关年龄、性别、病史、习惯、主观症状、临床类型、病变部位、组织学及治疗的数据。OLP患者占887例入院患者的20.1%。186例OLP患者中，130例（69.9%）为女性，56例（30.1%）为男性。诊断时的平均年龄为60.7岁（范围15 - 95岁）。仅24.2%的患者报告有吸烟习惯。OLP最常见的口腔表现为网状型（61.8%），其次是糜烂 - 大疱混合型（15%）和萎缩型（6.4%）。病理损害最常见于颊黏膜（89.2%）和舌（58.6%）。主观症状包括疼痛（48.4%）、烧灼感（46.2%）、口干（25.3%）、出血（10.2%）、味觉障碍（4.8%）和唾液分泌过多（3.8%），而22.6%的OLP患者无症状。波兰患者中最常见的OLP类型为网状型，主要发生于颊黏膜和舌。多见于不吸烟的中年女性。超过77%的患者有主观症状。
