Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Korean J Intern Med. 2010 Jun;25(2):207-12. doi: 10.3904/kjim.2010.25.2.207. Epub 2010 Jun 1.
BACKGROUND/AIMS: Antibiotic skin testing is a useful procedure for identifying patients with IgE-mediated hypersensitivity to antibiotics. The procedures, however, have not been standardized, and the testing is performed with diverse protocols in Korean hospitals wards. Thus, we examined the current practice of antibiotic skin testing in Korea.
We sent questionnaires to 12 allergists working in secondary or tertiary referral hospitals and collected them by e-mail or fax. The questionnaire included items such as the types and concentrations of the tested antibiotics, the methods of antibiotic skin testing, and the interpretation of the results.
All hospitals responded to the questionnaire. The antibiotic skin testing protocols were variable, inconsistent, and differed with regard to the type and concentrations of antibiotics, the volume injected, and the interpretation of the results. Moreover, the protocols differed from the commonly recommended procedures in the medical literature.
Standardized guidelines for antibiotic skin testing are needed for the safe and effective use of antibiotics in Korea.
背景/目的：抗生素皮肤试验是一种用于识别 IgE 介导的抗生素过敏患者的有用程序。然而，这些程序尚未标准化，并且在韩国医院病房中使用不同的方案进行测试。因此，我们检查了韩国目前的抗生素皮肤试验实践。
我们向在二级或三级转诊医院工作的 12 名过敏专家发送了问卷，并通过电子邮件或传真收集了问卷。问卷包括测试抗生素的类型和浓度、抗生素皮肤试验的方法以及结果的解释等项目。
所有医院都对问卷做出了回应。抗生素皮肤试验方案各不相同，不一致，并且在抗生素的类型和浓度、注射量以及结果解释方面存在差异。此外，这些方案与医学文献中推荐的常用程序不同。
需要为韩国抗生素的安全有效使用制定标准化的抗生素皮肤试验指南。
