Kammer B, Saini S, Brink J A, Knoefel W T, Ferrucci J T, Simeone J F, Mueller P R
Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Boston 02114.
Radiology. 1991 Jul;180(1):43-5. doi: 10.1148/radiology.180.1.2052720.
Injection cholecystography is often employed during invasive gallbladder procedures to determine the number of gallstones that are present. The authors undertook this study to define the optimal radiographic technique for performance of injection cholecystography. Condoms filled with 100 mL of contrast medium at four different iodine concentrations (30%, 15%, 7.5%, and 3.8% [wt/vol]) and containing up to five 4-mm-thick gallstones or a single 10-mm-thick gallstone were radiographed in a 20-cm-deep water bath by using four kilovolt peak settings (70, 80, 90, and 100 kVp). Images were read by three radiologists who were blinded to the radiographic technique. significantly (P less than .05) improved Decreasing iodine concentration significantly (P less than .05) improved detection of 4-mm-thick gallstones at a constant kilovolt peak setting. However, increasing the kilovolt peak setting while using the same concentration of contrast medium had no statistically significant influence on gallstone detectability, although radiologists did indicate a preference for the high-kilovolt peak technique. Results of the authors' experiments showed that for detection of small gallstones at injection cholecystography, use of a low-concentration contrast medium and a high kilovolt peak setting is the recommended radiographic technique.
在侵入性胆囊手术过程中，常采用注射胆囊造影术来确定存在的胆结石数量。作者开展这项研究以确定进行注射胆囊造影术的最佳放射照相技术。将装有100毫升四种不同碘浓度（30%、15%、7.5%和3.8%[重量/体积]）造影剂且含有多达五颗4毫米厚胆结石或一颗10毫米厚胆结石的避孕套，在20厘米深的水浴中使用四种千伏峰值设置（70、80、90和100 kVp）进行放射照相。由三位对放射照相技术不知情的放射科医生读取图像。在恒定的千伏峰值设置下，降低碘浓度可显著（P小于0.05）提高对4毫米厚胆结石的检测率。然而，在使用相同浓度造影剂的同时增加千伏峰值设置，对胆结石的可检测性没有统计学上的显著影响，尽管放射科医生确实表示偏爱高千伏峰值技术。作者的实验结果表明，在注射胆囊造影术中检测小胆结石时，推荐使用低浓度造影剂和高千伏峰值设置的放射照相技术。
