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宫颈癌同步化疗和盆腔放疗前通过卵巢移位保留卵巢功能。病例报告及文献综述。

Preservation of ovarian function by ovarian transposition prior to concurrent chemotherapy and pelvic radiation for cervical cancer. A case report and review of the literature.

作者信息

Bloemers M C W M, Portelance L, Legler C, Renaud M C, Tan S L

机构信息

Department of Radiotherapy, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

出版信息

Eur J Gynaecol Oncol. 2010;31(2):194-7.

Abstract

BACKGROUND

For over 45 years, ovarian transposition has been proposed for patients with cervical cancer to preserve ovarian function prior to pelvic radiation. We report a case of preservation of ovarian function and regular normal menstrual cycles after pelvic cisplatin-based chemoradiation and perform a literature review.

CASE

A 29-year-old female with cervical cancer underwent laparoscopic ovarian transposition prior to cisplatin-based chemoradiation. At 3-year follow-up after completion of her chemoradiation treatment indicated that she was still free of any disease. She is experiencing normal menstrual cycles at regular monthly intervals.

CONCLUSION

The present case shows that it is possible to retain ovarian function and menstrual cycles by ovarian transposition prior to pelvic chemoradiation. This provides an option for cervical cancer patients who desire preservation of ovarian function.

摘要

背景

45多年来,对于宫颈癌患者,一直有人提出在盆腔放疗前进行卵巢移位术以保留卵巢功能。我们报告了1例在基于顺铂的盆腔放化疗后卵巢功能得以保留且月经周期正常规律的病例,并进行了文献综述。

病例

1名29岁的宫颈癌女性在接受基于顺铂的放化疗前接受了腹腔镜下卵巢移位术。在完成放化疗3年后的随访显示,她仍未出现任何疾病。她的月经周期每月规律出现,正常无异常。

结论

本病例表明,盆腔放化疗前通过卵巢移位术有可能保留卵巢功能和月经周期。这为希望保留卵巢功能的宫颈癌患者提供了一种选择。

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