Center for Motility and Functional Gastrointestinal Disorders, Children's Hospital Boston, 300 Longwood Ave, Boston, MA 02155, USA.
Expert Rev Gastroenterol Hepatol. 2010 Jun;4(3):293-304. doi: 10.1586/egh.10.28.
Functional abdominal pain (FAP) and irritable bowel syndrome (IBS) are among the most commonly diagnosed medical problems in pediatrics. Symptom-based Rome III criteria for FAP and IBS have been validated and help the clinician in making a positive diagnosis. The majority of patients with mild complaints improve with reassurance and time. For a distinct subset of patients with more severe and disabling illness, finding effective treatment for these disorders remains a challenge. Over the years, a wide range of therapies have been proposed and studied. The lack of a single, proven intervention highlights the complex interplay of biopsychosocial factors probably involved in the development of childhood FAP and IBS, and the need for a multidisciplinary, integrated approach. This article reviews the current literature on the efficacy of pharmacologic, dietary and psychosocial interventions for FAP and IBS in children and adolescents.
功能性腹痛（FAP）和肠易激综合征（IBS）是儿科最常见的诊断性医学问题之一。基于症状的罗马 III 标准已被验证，可帮助临床医生做出阳性诊断。大多数轻度症状的患者通过安慰和时间的推移会有所改善。对于一组症状更严重和致残的特定患者，为这些疾病找到有效的治疗方法仍然是一个挑战。多年来，已经提出并研究了多种治疗方法。缺乏单一的、经过验证的干预措施，突出了生物心理社会因素的复杂相互作用，这些因素可能参与了儿童 FAP 和 IBS 的发展，并且需要多学科、综合的方法。本文综述了目前关于药物、饮食和心理社会干预治疗儿童和青少年 FAP 和 IBS 的疗效的文献。
