Florida International University, Department of Dietetics and Nutrition, Miami, Florida 33199, USA.
Int J Food Sci Nutr. 2010 Nov;61(7):690-701. doi: 10.3109/09637481003752267.
To examine whether dietary glycemic index (GI) or glycemic load (GL) had an effect on the cardiovascular disease (CVD) risk factors and whether the effects were dependent on the diabetes status in the Cuban American population.
A case–control, single-time-point study.
A total of 324 middle-aged Cuban American adults had completed data on fasting blood lipids, physical activity level and usual dietary intake using a validated food frequency questionnaire. Published GI values were assigned to food items and average dietary GI and GL were calculated per participant.
Subjects without type 2 diabetes (T2D) were 3.3 times more likely to be in the recommended, highest high-density lipoprotein-cholesterol category if they were in the second dietary GL tertile as compared with those in the first dietary GL tertile (P = 0.042, 95% confidence interval = 1.94, 10.78).
The results of the present study suggest that in this sample of Cuban Americans a high GI or GL diet do not adversely affects blood lipids, especially among subjects without T2D.
研究饮食血糖生成指数（GI）或血糖负荷（GL）是否会对心血管疾病（CVD）风险因素产生影响，以及这些影响是否取决于古巴裔美国人的糖尿病状况。
病例对照、单次时点研究。
共有 324 名中年古巴裔美国成年人完成了关于空腹血脂、身体活动水平和使用经过验证的食物频率问卷的常规饮食摄入的数据。为食物项目分配了已发表的 GI 值，并按每个参与者计算了平均饮食 GI 和 GL。
与第一 GL 三分位组相比，无 2 型糖尿病（T2D）的受试者如果处于第二 GL 三分位组，则更有可能处于推荐的最高高密度脂蛋白胆固醇类别（P=0.042，95%置信区间=1.94，10.78）。
本研究结果表明，在这个古巴裔美国人样本中，高 GI 或 GL 饮食不会对血脂产生不利影响，尤其是在无 T2D 的受试者中。
