Biomedical Engineering and Emergency Medicine, University of Virginia Health System, Charlottesville, VA, USA.
J Environ Pathol Toxicol Oncol. 2010;29(1):3-5. doi: 10.1615/jenvironpatholtoxicoloncol.v29.i1.20.
In this report, we describe the management of a multiple sclerosis patient with a femoral fracture who had severe vitamin D deficiency. After the patient's preoperative laboratory studies revealed a normal platelet count, the orthopedic surgeon performed an intramedullary rod fixation on the patient's left femoral fracture. After the surgery, the diagnosis of vitamin D deficiency was made by measuring the circulating serum concentration of 25-dihydroxyvita-min D (25(OH)D) via Disorin's Vitamin D immunochemiluminometric assay LIASION by LabCorp (Laboratory Corporation of America). The patient's postoperative management included the oral administration of 4000 IU of vitamin D3 in a gel-cap suspension that resulted in an elevation of the blood serum concentration of 25(OH)D to an optimal concentration of >80 nmol/L (32 ng/ml).
在本报告中，我们描述了一位多发性硬化症合并股骨骨折且严重维生素 D 缺乏症患者的治疗经过。在患者术前实验室检查显示血小板计数正常后，骨科医生对其左侧股骨骨折进行髓内棒固定。手术后，通过美国实验室公司的 Disorin 维生素 D 免疫化学发光测定法 LIASION 检测循环血清 25-羟维生素 D（25(OH)D）浓度，诊断为维生素 D 缺乏症。患者的术后治疗包括口服 4000IU 维生素 D3 凝胶胶囊，使血清 25(OH)D 浓度升高至最佳浓度>80nmol/L（32ng/ml）。
