Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK.
Addiction. 2010 Aug;105(8):1484-96. doi: 10.1111/j.1360-0443.2010.02981.x. Epub 2010 Jun 7.
To examine the longitudinal associations in both directions between mental health and substance use in adolescence.
Three-year longitudinal cohort.
Britain (nationally representative sample).
3607 youths aged 11-16 years at baseline.
Externalizing and internalizing mental health problems were measured using brief questionnaires (parent-reported Strengths and Difficulties Questionnaire) and diagnostic interviews, including clinician-rated diagnoses of mental disorder. Substance use was measured by youth self-report, and included regular smoking, frequent alcohol consumption, regular cannabis use and ever taking other illicit drugs.
Externalizing (specifically behavioural) problems at baseline independently predicted all forms of substance use, with a particularly strong effect on smoking. In all cases this association showed a dose-response relationship. In contrast, although internalizing problems had a strong univariable association with smoking, this disappeared after adjusting for comorbid externalizing problems. There was little or no evidence that baseline substance use predicted mental health at follow-up.
Externalizing problems predict adolescent substance use, and adjusting for comorbid externalizing problems is vital when investigating the effects of internalizing problems. A dose-response effect of externalizing problems is seen across the full range. Programmes seeking to prevent adolescent substance use by reducing externalizing problems may therefore wish to consider population-wide interventions rather than targeting individuals only at the negative extreme.
探讨青少年心理健康和物质使用之间在两个方向上的纵向关联。
为期三年的纵向队列研究。
英国(全国代表性样本)。
3607 名 11-16 岁的青少年。
使用简短问卷(家长报告的优点和困难问卷)和包括临床医生评定的精神障碍诊断在内的诊断访谈来测量外在和内在的心理健康问题。物质使用通过青少年自我报告来衡量,包括常规吸烟、频繁饮酒、常规大麻使用和曾经使用其他非法药物。
基线时的外在(特别是行为)问题独立预测了所有形式的物质使用,对吸烟的影响尤其强烈。在所有情况下,这种关联都显示出剂量反应关系。相比之下,尽管内在问题与吸烟有很强的单变量关联,但在调整了共病外在问题后,这种关联就消失了。几乎没有证据表明基线物质使用可以预测随访时的心理健康。
外在问题预测青少年物质使用,在调查内在问题的影响时,调整共病外在问题至关重要。外在问题的剂量反应效应在整个范围内都存在。因此,通过减少外在问题来预防青少年物质使用的项目可能希望考虑在整个人群中进行干预,而不是仅针对处于消极极端的个体。