Lindberg M
Department of Medical Biophysics, Karolinska Institute, Stockholm, Sweden.
Scanning Microsc. 1991 Mar;5(1):229-37; discussion 237-8.
Modern man is exposed to an increasing amount of chemicals in the environment. The skin is a complex tissue with regards to both structure and function. Contact with external stimuli can lead to various responses in the skin depending on the type of stimuli, the dose and time of exposure and the status of the exposed individual. The electron probe microanalytic technique can be used to obtain information on physiological alterations within the skin and especially the epidermis when the normal homeostasis is disturbed by contact with external stimuli. The present paper presents a review of some aspects of contact dermatitis and the possibility of using the electron probe microanalytic technique for analysis of epidermal events of this condition.
现代人接触到环境中越来越多的化学物质。皮肤在结构和功能方面都是一个复杂的组织。与外部刺激的接触会根据刺激的类型、接触的剂量和时间以及接触个体的状态，在皮肤中引发各种反应。当正常的内稳态因与外部刺激接触而受到干扰时，电子探针微分析技术可用于获取皮肤尤其是表皮内生理变化的信息。本文综述了接触性皮炎的某些方面，以及使用电子探针微分析技术分析这种疾病表皮事件的可能性。
