艾滋病毒感染对卢旺达女性身体组成和脂肪分布的影响。
Effect of HIV infection on body composition and fat distribution in Rwandan women.
作者信息
Mutimura Eugene, Anastos Kathryn, Cohen Mardge, Binagwaho Agnes, Kotler Donald P
机构信息
Women's Equity in Access to Care &Treatment, Kigali, Rwanda.
出版信息
J Int Assoc Physicians AIDS Care (Chic). 2010 May-Jun;9(3):173-8. doi: 10.1177/1545109710366472.
OBJECTIVE
To assess the association of HIV infection with body weight and composition in Rwandan women.
DESIGN
Body weight and composition, the latter determined by bioelectrical impedance analysis (BIA) and by anthropometry, were compared in 620 HIV-positive and 211 HIV-negative participants. Associations of HIV with body composition were assessed, and t tests compared the groups.
RESULTS
HIV-positive women were younger (-7.0 years, P < .001) and shorter (-2.1 cm, P < .001). Mean body weight, body mass index (BMI), total body fat, and waist-to-hip ratio (WHR) were similar. Mean fat-free mass was 2.5% greater in HIV-negative participants, and 19% of HIV-positive group had BMI <18.5 kg/m(2) versus 26% of the HIV-negative group (P < .05). CD4 counts and body composition were not associated.
CONCLUSIONS
Malnutrition was common in this cohort of Rwandan women. However, HIV infection was not associated with nutritional status. Factors other than malnutrition may influence quality-of-life outcomes in HIV-infected Rwandan women. Initiatives to improve nutritional status should be population-wide and not restricted to the HIV-infected population.
目的
评估卢旺达女性中HIV感染与体重及身体组成之间的关联。
设计
对620名HIV阳性参与者和211名HIV阴性参与者的体重及身体组成（后者通过生物电阻抗分析（BIA）和人体测量法测定）进行比较。评估HIV与身体组成的关联，并通过t检验对两组进行比较。
结果
HIV阳性女性更年轻（小7.0岁，P <.001）且更矮（矮2.1厘米，P <.001）。平均体重、体重指数（BMI）、全身脂肪和腰臀比（WHR）相似。HIV阴性参与者的平均去脂体重高2.5%，HIV阳性组中19%的人BMI<18.5 kg/m²，而HIV阴性组为26%（P <.05）。CD4细胞计数与身体组成无关联。
结论
在这组卢旺达女性中营养不良很常见。然而，HIV感染与营养状况无关。除营养不良外的其他因素可能会影响感染HIV的卢旺达女性的生活质量结果。改善营养状况的举措应针对全体人群，而不仅限于HIV感染人群。
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