Kobayashi H, Hayashi M, Kawano H, Handa Y, Kabuto M, Maeda H, Ishii Y
Department of Neurosurgery, Fukui Medical School, Japan.
Surg Neurol. 1991 Jun;35(6):436-40. doi: 10.1016/0090-3019(91)90176-a.
Eleven patients with occlusive cerebrovascular diseases were imaged with N-isopropyl-p-I-123 iodoamphetamine. Preoperative and postoperative single-photon emission computed tomography was performed in 10 patients undergoing extracranial-to-intracranial bypass procedures. New images were reconstructed from the two images obtained on the different days by superimposition and division in each pixel to get the ratio of cerebral perfusion change. All patients with bypass procedures had an increase in cerebral blood flow in the affected areas, and nine of 10 had an increase in cerebral blood flow in the contralateral cortex. There was no increase in cerebral blood flow in one case with no operation. Neither our procedure nor the results in this small series prove that recovery of function is due to an increase in blood flow, but we believe this is the case.
11例闭塞性脑血管疾病患者接受了N-异丙基-p-I-123碘安非他明成像检查。10例接受颅外-颅内搭桥手术的患者在术前和术后进行了单光子发射计算机断层扫描。通过在每个像素中叠加和分割在不同日期获得的两幅图像来重建新图像，以获得脑灌注变化的比率。所有接受搭桥手术的患者患侧脑血流量增加，10例中有9例对侧皮质脑血流量增加。1例未手术患者脑血流量未增加。我们的方法和这个小系列的结果都不能证明功能恢复是由于血流量增加，但我们认为情况就是如此。
