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肠易激综合征:营养干预能有效吗?

Irritable bowel syndrome: can nutrient manipulation help?

机构信息

Department of Gastroenterology, Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain.

出版信息

Curr Opin Clin Nutr Metab Care. 2010 Sep;13(5):581-7. doi: 10.1097/MCO.0b013e32833b6471.


DOI:10.1097/MCO.0b013e32833b6471
PMID:20531176
Abstract

PURPOSE OF REVIEW: To describe the evidences for the usefulness of dietary manipulations (including the use of probiotics and prebiotics) in the management of irritable bowel syndrome (IBS). RECENT FINDINGS: Exclusion diets do not have a role in the management of these patients except in the case of malabsorbed sugars (lactose, fructose). However, recent work suggests that excluding these sugars is more effective in non-IBS than in IBS patients. Also, the first small open series on the use of very low (20 g/day) carbohydrate diet (VLCD) in IBS has been published with promising results. However, safety concerns do not allow us to recommend them. In the period of review, further evidence has been provided on the role of psyllium in IBS. Also, the available evidence on the use of probiotics in IBS has been meta-analyzed. SUMMARY: IBS patients should eat a balanced diet without restrictions, and (except for malabsorbed sugars) exclusion diets are not useful in most of them. The role of VLCD remains to be established. The concept that increasing fiber intake is useful for IBS may not be true for all patients, and hydrophilic colloids (e.g. psyllium) are preferred. There is growing evidence for the effectiveness of probiotics in IBS.

摘要

目的综述:描述饮食干预(包括使用益生菌和益生元)在肠易激综合征(IBS)管理中的有效性证据。

最近的发现:排除饮食在这些患者的管理中没有作用,除了吸收不良的糖(乳糖、果糖)。然而,最近的研究表明,在非 IBS 患者中,排除这些糖比在 IBS 患者中更有效。此外,已经发表了关于极低(20 克/天)碳水化合物饮食(VLCD)在 IBS 中应用的首个小开放性系列研究,结果有希望。然而,安全性问题不允许我们推荐这种方法。在本综述期间,提供了更多关于车前子在 IBS 中的作用的证据。此外,对益生菌在 IBS 中的应用的现有证据进行了荟萃分析。

总结:IBS 患者应均衡饮食,无限制,大多数患者排除饮食没有作用。VLCD 的作用仍有待确定。增加纤维摄入对 IBS 有益的概念可能不适用于所有患者,亲水胶体(如车前子)是首选。益生菌对 IBS 的有效性有越来越多的证据支持。

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[1]
Efficacy of Dietary Interventions for Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis.

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[2]
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Front Nutr. 2021-6-15

[3]
Diarrhea Predominant-Irritable Bowel Syndrome (IBS-D): Effects of Different Nutritional Patterns on Intestinal Dysbiosis and Symptoms.

Nutrients. 2021-4-29

[4]
Effect of Three Diets (Low-FODMAP, Gluten-free and Balanced) on Irritable Bowel Syndrome Symptoms and Health-Related Quality of Life.

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[5]
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