Acute Care and Trauma Surgery Unit, Maggiore Hospital Trauma Center, L.go Nigrisoli 2, 40133 Bologna, Italy.
World J Surg. 2010 Sep;34(9):2064-8. doi: 10.1007/s00268-010-0667-1.
The Damage Control Surgery (DCS) approach to massive intraperitoneal hemorrhage has been shown to significantly reduce the morbidity and mortality in severely injured trauma patients. We applied the same principles to patients who developed a massive hemorrhage and the "lethal triad" (acidosis, hypothermia, coagulopathy) during a surgical procedure in order to assess feasibility and efficacy of DCS on nontraumatic grounds.
A retrospective analysis of eight consecutive cases was performed aimed at collecting information on laboratory parameters, fluids requirements, operative times, APACHE II score, damage control surgery procedure, angioembolization, morbidity, mortality, and need for repacking.
Average APACHE II score was 25.5 (predicted mortality rate = 54%); overall and early mortality in the nontraumatic group was nil, while the intra-abdominal septic (packing-related) complication rate was 12.5%.
Intra-abdominal packing was shown to be feasible, safe, and effective for patients with intra-abdominal nontraumatic massive hemorrhage, and the application of the principles of DCS may improve survival in cases of surgical hemorrhage with development of the lethal triad.
损伤控制外科(DCS)方法治疗腹腔内大出血已被证明可显著降低严重创伤患者的发病率和死亡率。我们将相同的原则应用于在手术过程中发生大出血和“致死三联征”(酸中毒、低体温、凝血功能障碍)的患者,以评估 DCS 在非创伤性基础上的可行性和疗效。
对连续 8 例患者进行回顾性分析,旨在收集实验室参数、液体需求、手术时间、急性生理和慢性健康评分(APACHE II)、损伤控制外科手术程序、血管栓塞、发病率、死亡率和重新填塞的需求等信息。
平均 APACHE II 评分为 25.5(预测死亡率=54%);非创伤性组的总死亡率和早期死亡率为零,而腹腔内感染(填塞相关)并发症发生率为 12.5%。
对于腹腔内非创伤性大出血的患者,腹腔内填塞是可行、安全和有效的,并且在发生致死三联征的手术性出血时应用 DCS 的原则可能会提高生存率。