Zadrazil J, Papajík T, Scudla V, Jezáková J, Budíková M, Slavícek J
Spojená katedra chorob vnitrních Univerzity Palackého, Olomouc.
Vnitr Lek. 1991 Apr;37(4):369-75.
The authors examined the iron level, total plasma iron binding capacity, serum ferritin, the red cell haemogram and iron reserves in bone marrow of 31 patients with chronic renal failure who had regular dialyzation treatment. In 24 patients (77%) they did not detect any iron reserves in bone marrow, 22 of these patients had serum ferritin levels lower than 100 micrograms/l. The authors found a significant correlation between serum ferritin and the iron reserves in bone marrow and confirmed that assessment of serum ferritin is the most reliable non-invasive method for assessment of iron deficiency of the organism. At the same time they draw attention to the fact that the serum ferritin concentration suggesting iron deficiency in haemodialyzed patients is higher.
作者对31例接受定期透析治疗的慢性肾衰竭患者的铁水平、总血浆铁结合能力、血清铁蛋白、红细胞血常规及骨髓铁储备进行了检查。在24例患者(77%)中,他们未在骨髓中检测到任何铁储备,其中22例患者的血清铁蛋白水平低于100微克/升。作者发现血清铁蛋白与骨髓铁储备之间存在显著相关性,并证实血清铁蛋白评估是评估机体缺铁最可靠的非侵入性方法。同时,他们提请注意这样一个事实,即提示血液透析患者缺铁的血清铁蛋白浓度更高。