Renggli M, Padrutt I, Michel E, Reichler I
Klinik für Fortpflanzungsmedizin der Universität Zürich.
Schweiz Arch Tierheilkd. 2010 Jun;152(6):279-84. doi: 10.1024/0036-7281/a000065.
Benign prostatic hyperplasia is a primarily non-inflammatory enlargement of the prostate due to proliferation of its epithelial and mesenchymal structures. These physiological alterations can be found in more than 95 % of aged intact male dogs, but common clinical symptoms as serosanguineous urethral discharge, haematuria, flattened faeces, constipation and tenesmus are only present in a few of them. In addition to surgical castration, hormonal suppression of testicular function with GnRH-depot-analogues, inhibition of the 5alpha-reductase or peripheral androgen action with anti-androgens are available today. This enables the clinician to find the optimal therapeutic strategy for each patient.
良性前列腺增生是由于前列腺上皮和间质结构增殖导致的前列腺主要非炎性肿大。这些生理改变可见于超过95%的老年未绝育雄性犬，但常见临床症状如浆液性血性尿道分泌物、血尿、粪便变扁、便秘和里急后重仅在少数犬中出现。除手术去势外，如今还可使用促性腺激素释放激素长效类似物抑制睾丸功能、5α还原酶抑制剂或抗雄激素抑制外周雄激素作用。这使临床医生能够为每位患者找到最佳治疗策略。
