National Agriculture and Food Research Organization, National Food Research Institute, Tsukuba, Ibaraki, Japan.
Int J Vitam Nutr Res. 2009 Sep;79(5-6):362-74. doi: 10.1024/0300-9831.79.56.362.
The aim of this study was to assess the interaction between physical and biochemical parameters in mice fed 1 % sea snake lipids (SSL) and compare these with animals fed diets containing 0.2 % green tea extract (GTE) or 0.5 % conjugated linoleic acid (CLA). The swimming times of the SSL group were significantly increased at Weeks 12 and 16 (p<0.001), and those of the GTE group, at Week 12 (p<0.005), but not those of the control or CLA group, compared with those at Week 0. The increase tended to be significant in the SSL group compared with the control group at Week 12 (p=0.09). Both the SSL and GTE groups had significantly longer swimming times than the CLA group at Weeks 12 and 16 (p<0.001). After 5 minutes of swimming exercise, the SSL group exhibited significantly lower levels of plasma and muscle lactates (p<0.01), and plasma non-esterified fatty acid (NEFA) (p<0.001) than the control group. There were no significant differences in any of plasma glucose, muscle and liver glycogens, muscle lactate dehydrogenase (LDH), carnitine palmitoyltransferase (CPT), or monocarboxylate transporter 1 (MCT1) between SSL and control groups. The results suggest that the intake of 1 % SSL improved endurance more than the intake of 0.2 % GTE or 0.5 % CLA in mice. This action may involve the promotion of lactate oxidation for utilization.
本研究旨在评估 1%海蛇脂（SSL）喂养的小鼠的物理和生化参数之间的相互作用，并将其与摄入 0.2%绿茶提取物（GTE）或 0.5%共轭亚油酸（CLA）的动物进行比较。SSL 组的游泳时间在第 12 周和第 16 周显著增加（p<0.001），GTE 组在第 12 周增加（p<0.005），但对照组和 CLA 组没有增加，与第 0 周相比。与对照组相比，SSL 组在第 12 周的增加趋势具有统计学意义（p=0.09）。与 CLA 组相比，SSL 组和 GTE 组在第 12 周和第 16 周的游泳时间明显更长（p<0.001）。游泳 5 分钟后，与对照组相比，SSL 组的血浆和肌肉乳酸水平显著降低（p<0.01），血浆非酯化脂肪酸（NEFA）水平显著降低（p<0.001）。血浆葡萄糖、肌肉和肝脏糖原、肌肉乳酸脱氢酶（LDH）、肉碱棕榈酰转移酶（CPT）或单羧酸转运蛋白 1（MCT1）在 SSL 组和对照组之间没有差异。结果表明，与摄入 0.2%GTE 或 0.5%CLA 相比，摄入 1%SSL 可提高小鼠的耐力。这种作用可能涉及促进乳酸氧化供能。
