Department of Food Science, Cornell University, Ithaca, NY, USA.
Int J Vitam Nutr Res. 2010 Jan;80(1):24-31. doi: 10.1024/0300-9831/a000003.
In the study presented, an in vitro digestion/Caco-2 cell culture model was used to assess the amount of bioavailable iron from a modified Tanzanian complementary food formulation. The main objective of the study was to determine whether a change from red beans to white beans in the complementary food recipe would improve iron bioavailability from the mixture, as recent studies had indicated that iron bioavailability in white beans is significantly higher compared to that in the colored beans. The white beans had a significantly higher (p<0.0001) amount of ferritin formation (13.54 ng/mg) when compared to all other porridge ingredients including the red beans (2.3 ng/mg), and it is plausible that the complementary food formulated with the white beans may be superior to that formulated with the red beans, with reference to iron bioavailability. The results are important as they suggest that substitution of complementary food ingredients with high anti-nutrient concentrations with those that have lower anti-nutrient concentrations may improve iron bioavailability from complementary food home-recipes.
在本研究中,采用体外消化/Caco-2 细胞培养模型来评估改良后的坦桑尼亚补充食品配方中生物可利用铁的含量。研究的主要目的是确定在补充食品配方中用白豆替代红豆是否会提高混合物中的铁生物利用率,因为最近的研究表明,白豆中铁的生物利用率明显高于有色豆。与其他所有粥类成分(包括红豆)相比,白豆形成的铁蛋白量(13.54ng/mg)明显更高(p<0.0001),因此,从铁生物利用率的角度来看,用白豆配制的补充食品可能优于用红豆配制的补充食品。研究结果很重要,因为它们表明,用抗营养物质浓度较低的补充食品成分替代高浓度的抗营养物质成分,可能会提高家庭自制补充食品中铁的生物利用率。