Centre for THz Waves, Ultrafast Laser Laboratory, College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, P.R. China.
J Biophotonics. 2010 Oct;3(10-11):641-5. doi: 10.1002/jbio.201000043.
Using terahertz time-domain spectroscopy (THz-TDS), we have investigated the THz spectra of astaxanthin and riboflavin and the spectra of two kinds of cell, haenatcoccus plusivalis and bacillus subtilis, which could produce astaxanthin and riboflavin, respectively, during their metabolite process. Riboflavin was found to be much more absorptive to THz radiation and have richer spectral characteristics than astaxanthin. As an intracellular metabolite, riboflavin could be distinguished from the cells by using THz-TDS. The technique has potential applications in high-throughput screening of industrial strains.
利用太赫兹时域光谱（THz-TDS），我们研究了虾青素和核黄素的太赫兹光谱，以及能够在代谢过程中分别产生虾青素和核黄素的两种细胞——血球藻和枯草芽孢杆菌的光谱。结果表明，核黄素对太赫兹辐射的吸收性更强，光谱特征也比虾青素更丰富。作为一种细胞内代谢产物，核黄素可以通过太赫兹时域光谱技术与细胞区分开来。该技术在工业菌株的高通量筛选中具有潜在的应用价值。
