Niesert S, Jakobi C, Behrens K, von zur Mühlen A
Frauenklinik, Medizinischen Hochschule, Hannover.
Z Geburtshilfe Perinatol. 1991 Jan-Feb;195(1):29-32.
In a prospective study the postpartum thyroid function was investigated in 120 healthy women in the department of obstetrics and gynecology of the Medical School Hannover. A physical examination was performed in the first week after delivery and two to five and five to eleven months later. Additionally blood was drawn for the determination of thyroid hormones, thyroid autoantibodies and thyroid-stimulating hormone. In 10% of the patients pathological titers for thyroid microsomal autoantibodies and thyroglobulin autoantibodies were found, in 2.5% pathological concentrations of thyroid hormones. In none of these patients clinical symptoms of thyroid dysfunction could be found. After delivery a immunologically mediated thyroid disease should be considered in patients with clinical symptoms. Then the thyroid function needs to be investigated.
在一项前瞻性研究中，对汉诺威医学院妇产科的120名健康女性的产后甲状腺功能进行了调查。在分娩后的第一周以及之后的两到五个月和五到十一个月进行了体格检查。此外，还采集了血液以测定甲状腺激素、甲状腺自身抗体和促甲状腺激素。在10%的患者中发现甲状腺微粒体自身抗体和甲状腺球蛋白自身抗体的滴度异常，在2.5%的患者中发现甲状腺激素浓度异常。在这些患者中均未发现甲状腺功能障碍的临床症状。分娩后，有临床症状的患者应考虑免疫介导的甲状腺疾病。然后需要对甲状腺功能进行调查。
