基于尿液的脂阿拉伯甘露聚糖检测在结核病患者中的定量分析。
Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosis.
机构信息
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
出版信息
J Clin Microbiol. 2010 Aug;48(8):2972-4. doi: 10.1128/JCM.00363-10. Epub 2010 Jun 9.
Abstract
Urinary lipoarabinomannan (LAM) detection is a promising approach for rapid diagnosis of active tuberculosis (TB). In microbiologically confirmed TB patients, quantitative LAM detection results increased progressively with bacillary burden and immunosuppression. Patients with disseminated TB and/or advanced HIV are target populations for whom urine LAM detection may be particularly useful.
摘要
尿脂阿拉伯甘露聚糖（LAM）检测是一种有前途的快速诊断活动性肺结核（TB）的方法。在微生物学确诊的 TB 患者中，定量 LAM 检测结果随细菌负担和免疫抑制的增加而逐渐增加。患有播散性 TB 和/或晚期 HIV 的患者是该检测方法特别有用的目标人群。
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