• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠幼崽出生后早期发育阶段进行触须切除对行为发育的影响。

Effects of vibrissectomy during early postnatal ontogenesis in rat pups on behavioral development.

作者信息

Shishelova A Y, Raevskii V V

机构信息

Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, Russia.

出版信息

Neurosci Behav Physiol. 2010 Jul;40(6):671-7. doi: 10.1007/s11055-010-9310-8. Epub 2010 Jun 11.

DOI:10.1007/s11055-010-9310-8
PMID:20535568
Abstract

The effects of daily trimming of the whiskers in rat pups from day 2 or day 9 to day 20 on eye opening time and the formation of early behavioral reactions, i.e., walking, rearing, grooming, and manipulatory activity, were studied in rat pups subjected to deprivation and siblings reared with them. Rat pups subjected to vibrissectomy from day 2 of life and their siblings showed acceleration of eye opening, maturation of grooming, and rearing without support; the formation of manipulatory activity was delayed, as were changes in the structures of correlational relationships between the times at which behavioral reactions formed and eye opening occurred. Vibrissectomy from day 9 of life eliminated most correlational relationships in deprived animals without impairing the dynamics of the development of early behavioral reactions. Siblings showed delayed formation of manipulatory activity, though changes in the structure of correlational relationships were less significant than in deprived animals.

摘要

研究了从出生第2天或第9天到第20天每天修剪幼鼠胡须对睁眼时间以及早期行为反应(即行走、站立、梳理毛发和操控活动)形成的影响,实验对象为经历胡须切除的幼鼠及其一同饲养的同胞幼鼠。出生第2天接受胡须切除的幼鼠及其同胞幼鼠表现出睁眼加速、梳理毛发成熟以及无需支撑就能站立;操控活动的形成延迟,行为反应形成时间与睁眼时间之间的相关关系结构变化也延迟。出生第9天进行胡须切除消除了剥夺组动物的大多数相关关系,但不影响早期行为反应的发育动态。同胞幼鼠表现出操控活动形成延迟,不过相关关系结构的变化不如剥夺组动物显著。

相似文献

1
Effects of vibrissectomy during early postnatal ontogenesis in rat pups on behavioral development.大鼠幼崽出生后早期发育阶段进行触须切除对行为发育的影响。
Neurosci Behav Physiol. 2010 Jul;40(6):671-7. doi: 10.1007/s11055-010-9310-8. Epub 2010 Jun 11.
2
[Influence of vibrissectomy in early postnatal ontogeny of rat pups on behavioral development].[大鼠幼崽出生后早期本体发育中切除触须对行为发育的影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 2009 May-Jun;59(3):326-34.
3
Developmental milestones and behavior of infant rats: The role of sensory input from whiskers.婴儿鼠的发育里程碑和行为:胡须感觉输入的作用。
Behav Brain Res. 2019 Nov 18;374:112143. doi: 10.1016/j.bbr.2019.112143. Epub 2019 Aug 6.
4
Effect of whisker removal on defensive behavior in rats during early ontogenesis.触须去除对大鼠早期个体发育过程中防御行为的影响。
Neurosci Behav Physiol. 2006 Oct;36(8):883-8. doi: 10.1007/s11055-006-0102-0.
5
Neonatal whisker trimming in WAG/Rij rat pups causes developmental delay, encourages maternal care and affects exploratory activity in adulthood.新生 WAG/Rij 大鼠胡须修剪可导致发育迟缓,促进母性行为,并影响成年后的探索活动。
Brain Res Bull. 2018 Jun;140:120-131. doi: 10.1016/j.brainresbull.2018.04.010. Epub 2018 Apr 21.
6
[The experience of maternity exerts a significant effect on the shaping of behavior in rat progeny in early postnatal ontogeny].[母体经历对出生后早期个体发育阶段大鼠后代行为的形成具有显著影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1999 Jan-Feb;49(1):68-76.
7
[The effect of early sensory experience on development of neuron functional properties in the area of vibrissal projection in the rat neocortex].[早期感觉经验对大鼠新皮质触须投射区神经元功能特性发育的影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 2010 Nov-Dec;60(6):719-29.
8
Defining the relationship between maternal care behavior and sensory development in Wistar rats: Auditory periphery development, eye opening and brain gene expression.定义母性行为与 Wistar 大鼠感觉发育的关系:听觉外围发育、睁眼和大脑基因表达。
PLoS One. 2020 Aug 21;15(8):e0237933. doi: 10.1371/journal.pone.0237933. eCollection 2020.
9
[The behavioral development of rats with prenatal hypoinsulinemia].[产前低胰岛素血症大鼠的行为发育]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1995 Nov-Dec;45(6):1190-7.
10
Parents' adulthood stress induces behavioral and hormonal alterations in male rat offspring.父母的成年期压力会导致雄性幼鼠的行为和激素变化。
Behav Brain Res. 2013 Sep 1;252:136-43. doi: 10.1016/j.bbr.2013.05.026. Epub 2013 May 25.

引用本文的文献

1
The pattern of thalamocortical and brain stem projections to the vibrissae-related sensory and motor cortices in de-whiskered congenital hypothyroid rats.去须先天性甲状腺功能减退大鼠中,丘脑皮质和脑干向触须相关感觉和运动皮质投射的模式。
Metab Brain Dis. 2017 Aug;32(4):1223-1235. doi: 10.1007/s11011-017-0027-z. Epub 2017 May 11.
2
Sensory deprivation during early development causes an increased exploratory behavior in a whisker-dependent decision task.早期发育过程中的感觉剥夺会导致在依赖于胡须的决策任务中增加探索行为。
Brain Behav. 2013 Jan;3(1):24-34. doi: 10.1002/brb3.102. Epub 2012 Nov 29.

本文引用的文献

1
Effects of early binocular enucleation on auditory and somatosensory coding in the superior colliculus of the rat.早期双眼摘除对大鼠上丘听觉和体感编码的影响。
Brain Res. 2008 Jan 29;1191:84-95. doi: 10.1016/j.brainres.2007.11.003. Epub 2007 Nov 12.
2
Retinal influences induce bidirectional changes in the kinetics of N-methyl-D-aspartate receptor-mediated responses in striate cortex cells during postnatal development.视网膜影响在出生后发育过程中诱导纹状皮层细胞中N-甲基-D-天冬氨酸受体介导反应动力学的双向变化。
Neuroscience. 2007 Sep 7;148(3):683-99. doi: 10.1016/j.neuroscience.2007.07.005. Epub 2007 Jul 12.
3
Huddling by rat pups: ontogeny of individual and group behavior.
大鼠幼崽的蜷缩行为:个体及群体行为的个体发生学
Dev Psychobiol. 2007 Jan;49(1):22-32. doi: 10.1002/dev.20190.
4
Early deprivation increases exploration and locomotion in adult male Wistar offspring.早期剥夺会增加成年雄性Wistar后代的探索行为和运动能力。
Pharmacol Biochem Behav. 2006 Nov;85(3):535-44. doi: 10.1016/j.pbb.2006.10.005. Epub 2006 Nov 15.
5
Development of rodent macrovibrissae: effects of neonatal whisker denervation and bilateral neonatal enucleation.啮齿动物大触须的发育:新生触须去神经支配和双侧新生去眼球术的影响。
Somatosens Mot Res. 2006 Mar-Jun;23(1-2):11-7. doi: 10.1080/08990220600700784.
6
Development of rodent whisking: trigeminal input and central pattern generation.啮齿动物触须运动的发育:三叉神经输入与中枢模式生成。
Somatosens Mot Res. 2006 Mar-Jun;23(1-2):1-10. doi: 10.1080/08990220600700768.
7
[Effect of vibrissae removal on the defensive behavior of rats in early ontogeny].
Zh Vyssh Nerv Deiat Im I P Pavlova. 2005 Sep-Oct;55(5):677-83.
8
Whisker trimming begun at birth or on postnatal day 12 affects excitatory and inhibitory receptive fields of layer IV barrel neurons.出生时或出生后第12天开始的触须修剪会影响IV层桶状神经元的兴奋性和抑制性感受野。
J Neurophysiol. 2005 Dec;94(6):3987-95. doi: 10.1152/jn.00569.2005. Epub 2005 Aug 10.
9
Influence of visual experience on developmental shift from long-term depression to long-term potentiation in the rat medial vestibular nuclei.视觉经验对大鼠内侧前庭核中从长时程抑制向长时程增强转变的发育影响。
J Physiol. 2004 Nov 1;560(Pt 3):767-77. doi: 10.1113/jphysiol.2004.069658. Epub 2004 Aug 26.
10
Variations in maternal care in the rat as a mediating influence for the effects of environment on development.大鼠母体护理的变化作为环境对发育影响的中介因素。
Physiol Behav. 2003 Aug;79(3):359-71. doi: 10.1016/s0031-9384(03)00149-5.