Miura Satoru, Yamamoto Nobuyuki
Division of Thoracic Oncology, Shizuoka Cancer Center.
Nihon Rinsho. 2010 Jun;68(6):1121-8.
Lung cancer is treated with surgery, radiotherapy and chemotherapy according to histology and clinical stage. Advanced stage lung cancer patients cannot be cured, but early and locally-advanced stage patients can be cured by intensive combined-modality therapy. Combined-modality therapy with surgery plus adjuvant chemotherapy is standard for resectable IB-IIIA non-small cell lung cancer (NSCLC) and stage I small cell lung cancer (SCLC) patients. Chemoradiotherapy is standard for unresectable locally-advanced NSCLC and limited-stage SCLC patients. Recently, several new drugs, molecular targeted drugs, have become available for clinical use and trials. We reviewed standard and new strategy of combined-modality therapy for early and locally-advanced lung cancer patients.
肺癌根据组织学类型和临床分期采用手术、放疗和化疗进行治疗。晚期肺癌患者无法治愈，但早期和局部晚期患者可通过强化综合治疗治愈。手术加辅助化疗的综合治疗是可切除的IB-IIIA期非小细胞肺癌（NSCLC）和I期小细胞肺癌（SCLC）患者的标准治疗方法。放化疗是不可切除的局部晚期NSCLC和局限期SCLC患者的标准治疗方法。最近，几种新药，即分子靶向药物，已可用于临床使用和试验。我们回顾了早期和局部晚期肺癌患者综合治疗的标准和新策略。
