Department of Pharmaceutical Sciences, HNB Garhwal University Srinagar (Garhwal), Uttarakhand, India.
J Dermatolog Treat. 2011 Jun;22(3):123-32. doi: 10.3109/09546630903578574. Epub 2010 Jun 10.
Hair has psychological and sociological importance throughout the ages in framing the personality and general appearance of an individual. Significant progress is being made on discovering an effective and safe drug for hair growth. Angiogenesis, androgen antagonism, vasodilation, potassium channel opening and 5-alpha reductase inhibition are the major non-surgical therapeutic strategies of hair growth promotion. In spite of a flood of drugs claiming to be useful as hair growth promoters, more rational strategies, which can target the problem areas or stages of the hair growth cycle effectively, are still awaited. This article highlights the developments in hair rejuvenation strategies and reviews the potential of herbal drugs as safer and effective alternatives.
自古以来,头发在塑造个人的个性和整体形象方面具有心理和社会学上的重要性。在发现有效和安全的生发药物方面取得了重大进展。血管生成、雄激素拮抗、血管扩张、钾通道开放和 5-α 还原酶抑制是促进毛发生长的主要非手术治疗策略。尽管有大量声称对促进头发生长有用的药物,但仍需要更合理的策略,这些策略可以有效地针对头发生长周期的问题区域或阶段。本文强调了头发再生策略的发展,并回顾了草药药物作为更安全和有效的替代品的潜力。