School of Medicine, University of Southampton, Southampton, UK.
Diabet Med. 2010 Mar;27(3):354-9. doi: 10.1111/j.1464-5491.2010.02951.x.
To determine whether there have been changes in glycaemic control and lipids in a cohort of people with repeated glycated haemoglobin (HbA(1c)) measurements since the implementation of the Quality and Outcomes Framework (QOF) for diabetes care.
Retrospective retrieval of computer-held biochemical measurements of glycaemic control (HbA(1c)) and lipid profiles in adults in Hampshire, UK between 2006 and 2008. Routine data on age, sex, HbA(1c) and plasma lipids were available on an NHS database on 8997 adults with data available for HbA(1c) in both 2006 and 2008.
In 2006, 39.7% of adults had glycaemic control within the QOF threshold (HbA(1c) < 7.5%); by 2008, this proportion had risen to 52.1% (P < 0.001). In 2006, 11.8% of subjects had poor glycaemic control (HbA(1c) > 10.0%); by 2008, this proportion had decreased to 10.1% (P < 0.001). The proportion of subjects achieving HbA(1c) and cholesterol targets (both HbA(1c) < 7.5% and total cholesterol < or = 5.0 mmol/l) was 30.2% in 2006; in 2008, this proportion had increased to 43.7% (P < 0.001). Individuals with poorer glycaemic control (HbA(1c) > 10.0%) were younger and had higher cholesterol concentrations than people with good (HbA(1c) < 7.5%) or moderate (HbA(1c) 7.5-10.0%) glycaemic control (P value for trend, both P < 0.001).
Since the introduction of performance indicators for primary care and the incorporation of pay for performance in 2004, there has been marked improvement in the management of hyperglycaemia and hypercholesterolaemia among people with diabetes with data available in 2006 and 2008. It remains to be seen whether the new HbA(1c) audit target (HbA(1c) < 7.0%) introduced in 2009 will result in a further improvement in glycaemic control.
自 2004 年实施糖尿病护理质量和结果框架(QOF)以来,通过重复测量糖化血红蛋白(HbA1c),确定人群的血糖控制和血脂变化情况。
检索 2006 年至 2008 年英国汉普郡成年人的血糖控制(HbA1c)和血脂概况的计算机生化测量值。在 NHS 数据库中可以获得关于 8997 名成年人的常规数据,包括年龄、性别、HbA1c 和血浆脂质,这些数据中 2006 年和 2008 年均有 HbA1c 数据。
2006 年,39.7%的成年人血糖控制达到 QOF 阈值(HbA1c<7.5%);到 2008 年,这一比例上升至 52.1%(P<0.001)。2006 年,11.8%的患者血糖控制不佳(HbA1c>10.0%);到 2008 年,这一比例下降至 10.1%(P<0.001)。HbA1c 和胆固醇目标(HbA1c<7.5%和总胆固醇<或=5.0mmol/L)均达到的患者比例在 2006 年为 30.2%;2008 年,这一比例上升至 43.7%(P<0.001)。血糖控制较差(HbA1c>10.0%)的患者比血糖控制良好(HbA1c<7.5%)或中等(HbA1c7.5-10.0%)的患者年龄更小,胆固醇浓度更高(P 值趋势均<0.001)。
自 2004 年引入初级保健绩效指标并将绩效薪酬纳入其中以来,有数据可查的 2006 年和 2008 年,糖尿病患者的高血糖和高胆固醇血症管理得到显著改善。2009 年引入的新 HbA1c 审计目标(HbA1c<7.0%)是否会进一步改善血糖控制,还有待观察。