Parasitology-Mycology Department, J Minjoz University Hospital, Besançon, France.
J Travel Med. 2010 May-Jun;17(3):201-2. doi: 10.1111/j.1708-8305.2009.00395.x.
We present a case of severe malaria due to Plasmodium malariae. Genetic testing showed that the patient was homozygous for five important gene polymorphisms previously shown to be associated with increased susceptibility to, and/or severity of, severe sepsis. Our case suggests that P. malariae may cause life-threatening disease, and that disease severity may be linked, at least in part, to multiple susceptibility genes.
我们报告了一例由间日疟原虫引起的严重疟疾。基因检测显示，该患者五个重要基因多态性纯合，这些多态性先前与严重脓毒症的易感性增加和/或严重程度增加有关。我们的病例提示间日疟原虫可能引起危及生命的疾病，且疾病严重程度至少部分与多个易感性基因有关。
